Despite the beneficial properties and outstanding potential of hydrogels for biomedical
applications, several unmet challenges must be overcome, especially regarding to their known …

In the last years, nanostructured biomaterials have raised a great interest as platforms for
delivery of drugs, genes, imaging agents and for tissue engineering applications. In particular, …

Although contact lenses are promising platforms for ocular drug delivery and have been
extensively studied for that purpose, the influence of sterilization methods on these systems …

The use of flubendazole (FBZ) in the treatment of lymphatic filariasis and onchocerciasis (two
high incidence neglected tropical diseases) has been hampered by its poor aqueous …

Sterilization of hydrogels is challenging due to their often reported sensitivity to conventional
methods involving heat or radiation. Although aseptic manufacturing is a possibility, …

The standard, quantitative determination of neomycin activity by the agar diffusion method
requires an 18 to 24 h incubation time. To reduce incubation time, an alternative method using …

Com o intuito de buscar uma nova alternativa para o tratamento das infecções do ambiente
bucal, o trabalho propôs a utilização de comprimidos bucais adesivos contendo acetato de …

The aim of this study was to validate an agar diffusion method through the parameters linearity,
precision and accuracy, to quantify apramycin in soluble powder. The calibration curve of …

Durante os últimos 25 anos, numerosos estudos têm sido efetuados visando a biocompatibilidade
de materiais de uso médico-hospitalar. Isto se deve ao desenvolvimento de materiais …

Pharmaceutical equivalence is an important step towards the confirmation of similarity and
interchangeability among pharmaceutical products, particularly regarding those that will not …