Campylobacter jejuni Cytolethal Distending Toxin Mediates Release of Interleukin-8 from Intestinal Epithelial Cells

TE Hickey, AL McVeigh, DA Scott… - Infection and …, 2000 - Am Soc Microbiol
Live cells of Campylobacter jejuni andCampylobacter coli can induce release of interleukin-8
(IL-8) from INT407 cells. Additionally, membrane fractions of C. jejuni 81-176, but not …

Phase Variation of Campylobacter jejuni 81-176 Lipooligosaccharide Affects Ganglioside Mimicry and Invasiveness In Vitro

…, CM Szymanski, MM Prendergast, TE Hickey… - Infection and …, 2002 - Am Soc Microbiol
The outer cores of the lipooligosaccharides (LOS) of many strains of Campylobacter jejuni
mimic human gangliosides in structure. A population of cells of C. jejuni strain 81-176 …

Sialylation of Lipooligosaccharide Cores Affects Immunogenicity and Serum Resistance of Campylobacter jejuni

P Guerry, CP Ewing, TE Hickey… - Infection and …, 2000 - Am Soc Microbiol
Three genes involved in biosynthesis of the lipooligosaccharide (LOS) core of Campylobacter
jejuni MSC57360, the type strain of the HS:1 serotype, whose structure mimics GM 2 …

DNA Sequence and Mutational Analyses of the pVir Plasmid of Campylobacter jejuni 81-176

DJ Bacon, RA Alm, L Hu, TE Hickey… - Infection and …, 2002 - Am Soc Microbiol
The circular pVir plasmid of Campylobacter jejuni strain 81-176 was determined to be 37,468
nucleotides in length with a G+C content of 26%. A total of 83% of the plasmid represented …

Campylobacter jejuni-Stimulated Secretion of Interleukin-8 by INT407 Cells

TE Hickey, S Baqar, AL Bourgeois, CP Ewing… - Infection and …, 1999 - Am Soc Microbiol
Incubation of INT407 cells with various clinical isolates ofCampylobacter jejuni resulted in
secretion of interleukin-8 (IL-8) at levels ranging from 96 to 554 pg/ml at 24 h. The strains …

[HTML][HTML] Intracellular Survival of Campylobacter jejuni in Human Monocytic Cells and Induction of Apoptotic Death by Cytholethal Distending Toxin

TE Hickey, G Majam, P Guerry - Infection and immunity, 2005 - Am Soc Microbiol
Campylobacter jejuni 81-176 is capable of extensive replication within human monocytic
cell vacuoles and induces apoptotic death via cytolethal distending toxin.

Heterogeneity of a Campylobacter jejuni Protein That Is Secreted through the Flagellar Filament

F Poly, C Ewing, S Goon, TE Hickey… - Infection and …, 2007 - Am Soc Microbiol
Cj0859c, or FspA, is a small, acidic protein of Campylobacter jejuni that is expressed by a σ
28 promoter. Analysis of the fspA gene in 41 isolates of C. jejuni revealed two overall …

Binding and neutralization of lipopolysaccharides by plant proanthocyanidins

JB Delehanty, BJ Johnson, TE Hickey… - Journal of Natural …, 2007 - ACS Publications
Proanthocyanidins (PACs), polyphenolic metabolites that are widely distributed in higher
plants, have been associated with potential positive health benefits including antibacterial, …

Antiviral properties of cobalt (III)-complexes

…, JE Bongard, DC Thach, DA Knight, TE Hickey… - Bioorganic & medicinal …, 2008 - Elsevier
We have investigated the potential antiviral activity of three cobalt(III) compounds. Two
compounds, Co(III)–cyclen–methylbenzoic acid and its methyl ester derivative, are based on the …

Campylobacter jejuni Induces Secretion of Proinflammatory Chemokines from Human Intestinal Epithelial Cells

L Hu, TE Hickey - Infection and immunity, 2005 - Am Soc Microbiol
Campylobacter jejuni is a common cause of diarrhea in humans. While the pathogenic
mechanisms of C. jejuni are not completely understood, host inflammatory responses are thought …