[HTML][HTML] A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults

…, EC Wright, TG Baumgartner… - … England Journal of …, 1992 - Mass Medical Soc
Background. Mortality is very high in lactic acidosis, and there is no satisfactory treatment
other than treatment of the underlying cause. Uncontrolled studies have suggested that …

Natural history and course of acquired lactic acidosis in adults

PW Stacpoole, EC Wright, TG Baumgartner… - The American journal of …, 1994 - Elsevier
study objective: To determine the pathogenesis and clinical course of lactic acidosis in adults
receiving standard medical care. design: Placebo arm of a 5-year prospective, randomized…

Treatment of lactic acidosis with dichloroacetate

…, EM Harman, SH Curry, TG Baumgartner… - … England Journal of …, 1983 - Mass Medical Soc
We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals and
lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of various …

[HTML][HTML] Primed, constant infusion with [2H3] serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes …

…, B Shane, JP Toth, TG Baumgartner… - The American journal of …, 2000 - Elsevier
Background: One-carbon metabolism involves both mitochondrial and cytosolic forms of
folate-dependent enzymes in mammalian cells, but few in vivo data exist to characterize the …

Bioavailability of pyridoxine-5′-β-D-glucoside determined in humans by stable-isotopic methods

…, PR Trumbo, LB Bailey, JP Toth, TG Baumgartner… - The Journal of …, 1991 - Elsevier
Stable-isotopic methods were employed to evaluate the utilization of dietary pyridoxine-5′-β-D-glucoside
(PN-glucoside), a major form of vitamin B-6 in plant-derived foods, as a …

Deficiencies of folate and vitamin B6 exert distinct effects on homocysteine, serine, and methionine kinetics

…, J Williamson, TG Baumgartner… - American Journal …, 2001 - journals.physiology.org
Folate and vitamin B 6 act in generating methyl groups for homocysteine remethylation, but
the kinetic effects of folate or vitamin B 6 deficiency are not known. We used an intravenous …

Relative bioavailability of deuterium-labeled monoglutamyl tetrahydrofolates and folic acid in human subjects

…, LB Bailey, JP Toth, TG Baumgartner… - The American journal of …, 1992 - Elsevier
The bioavailability of orally administered monoglutamyl folic acid and various (6S)-tetrahydrofolates
was examined in humans with stable-isotope methods. Folic acid (PteGlu), …

Plasma concentrations and metabolic effects of intravenous sodium dichloroacetate

SH Curry, PI Chu, TG Baumgartner… - Clinical …, 1985 - Wiley Online Library
Eleven healthy subjects received five doses of intravenous sodium dichloroacetate (DCA) at
2‐hr intervals. Determinations of DCA in plasma and of lactate and glucose in blood were …

Relative bioavailability of deuterium-labeled monoglutamyl and hexaglutamyl folates in human subjects

…, LB Bailey, JP Toth, TG Baumgartner… - The American journal of …, 1991 - Elsevier
The bioavailability of orally administered mono- and polyglutamyl folates was examined in
humans by using stable-isotope methods. [3',5'- 2 H 2 ]Folic acid (d2-FA) and [3',5'- 2 H 2 ]…

Bacterial endotoxin retention by inline intravenous filters

TG Baumgartner, GL Schmidt… - American journal of …, 1986 - academic.oup.com
Filters used in iv administration sets were tested for their ability to retain bacterial endotoxins
for up to 96 hours of continuous infusion. Inline filters composed of cellulose ester, …