The water flow rates of commercial sterilizing grade 10″ filter cartridges were simulated by
Computational Fluid Dynamics (CFD) and compared to experimental data. This study …

This publication describes the development of an experimental set-up and testing protocol
to test the hypothesis that filters used for sterile filtration can act as scavengers of leachables. …

Fluid flow rate and total throughput are the major controlling parameters to calculate the
required size of membrane-based filter equipment for manufacturing of pharmaceuticals. …

Cytotoxic drugs can be encapsulated in liposomes vesicles, which act as drug delivery
vehicles and reduce the risk of exposure of drug to healthy cells. The sterility of such liposome …

Sterile filters are ubiquitous in biopharmaceutical manufacturing processes. Because such
filters are in direct contact with the process fluid, profiling of the extractables is of utmost …

Filtration is universally used in biopharmaceutical processing. For example, in upstream
processing for sterilizing-grade filtration of cell culture media or in various downstream …

The article contains sections titled: 1. Terminology 2. Filtration Models 2.1. Calculation of the
Pressure Drop over the Filter Medium and/or the Filter Cake 2.1.1. Definition of Filter …

Users of single-use (SU) components need extractables data to demonstrate material safety
for regulatory bodies before incorporation in the biopharmaceutical process. In this context, …

Scalability of filter throughput in normal flow filtration runs is an important consideration in
the development of biopharmaceutical downstream processes. Depending on the filtration …

Cytotoxic drugs can be encapsulated in liposomes vesicles, which act as drug delivery vehicles
and reduce the risk of exposure of drug to healthy cells(1). The sterility of such liposome …