The use of TOC reconciliation as a means of establishing the degree to which chromatographic screening of plastic material extracts for organic extractables is …

D Jenke, TR Couch, SJ Robinson, TJ Volz… - PDA Journal of …, 2014 - journal.pda.org
Extracts of plastic packaging, manufacturing, and delivery systems (or their materials of
construction) are analyzed by chromatographic methods to establish the system's extractables …

Effect of route of inoculation on experimental respiratory viral disease in volunteers and evidence for airborne transmission

RB Couch, TR Cate, RG Douglas Jr… - Bacteriological …, 1966 - Am Soc Microbiol
Medicine, Houston, Tex. 2Present address: Washington University College of Medicine, St.
Louis, Mo. deposit predominantly in the lower respiratory tract. Particles between 5 and 15 …

Efficacy of repeated annual immunization with inactivated influenza virus vaccines over a five year period

WA Keitel, TR Cate, RB Couch, LL Huggins, KR Hess - Vaccine, 1997 - Elsevier
Some reports have suggested that influenza virus vaccine is less effective in persons that
have received prior annual vaccination(s) than in those receiving it for the first time. This issue …

Safety and immunogenicity of a high dosage trivalent influenza vaccine among elderly subjects

RB Couch, P Winokur, R Brady, R Belshe, WH Chen… - Vaccine, 2007 - Elsevier
To improve immune responses to influenza vaccine, a trivalent inactivated vaccine containing
60μg of the HA of each component (A/H3N2, A/H1N1, B) was compared to a licensed …

Safety of high doses of influenza vaccine and effect on antibody responses in elderly persons

…, SB Greenberg, F Ruben, RB Couch - Archives of internal …, 2006 - jamanetwork.com
Background Immune responses after influenza immunization are reduced in elderly individuals,
the group at greatest risk for complications and death after influenza. Improved vaccines …

Reactogenicity, immunogenicity, and antibody persistence in adults given inactivated influenza virus vaccines—1978

TR Cate, RB Couch, D Parker… - Reviews of infectious …, 1983 - academic.oup.com
Monovalent A/USSR/77 (H1N1) and trivalent A/USSR/77, A/Texas/77 (H3N2), and B/Hong
Kong/72 influenza virus vaccines from four manufacturers were tested in 292 adult volunteers…

A high dosage influenza vaccine induced significantly more neuraminidase antibody than standard vaccine among elderly subjects

…, R Brady, R Belshe, W Chen, RL Atmar, RB Couch - Vaccine, 2010 - Elsevier
Antibody to the neuraminidase (NA) antigen of influenza viruses has been shown to correlate
with immunity to influenza in humans and animal models. In a previous report, we showed …

Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations

…, J Pompey, TR Cate, RB Couch - Clinical infectious …, 2006 - academic.oup.com
Background . Influenza A/H9N2 viruses can infect humans and are considered to be a
pandemic threat. Effective vaccines are needed for these and other avian influenza viruses. …

Immunization with types 4 and 7 adenovirus by selective infection of the intestinal tract

RB Couch, RM Chanock, TR Cate, DJ Lang… - American Review of …, 1963 - atsjournals.org
Adenoviral infection is now known to be an important cause of illness in civilian and military
populations. Studies in civilian populations have shown that approximately 5 to 10 per cent …

Purified influenza A virus N2 neuraminidase vaccine is immunogenic and non-toxic in humans

ED Kilbourne, RB Couch, JA Kasel, WA Keitel, TR Cate… - Vaccine, 1995 - Elsevier
The immunogenicity and toxicity of a purified influenza virus (N2) neuraminidase vaccine (NAV)
were investigated in 88 human subjects aged 18–40, and compared to response to a …