User profiles for Tim Sandle

Tim Sandle

Head of Microbiology / Compliance, BPL; visiting tutor, University of Manchester; tutor at …
Verified email at bpl.co.uk
Cited by 2879

A review of cleanroom microflora: types, trends, and patterns

T Sandle - PDA Journal of pharmaceutical science and …, 2011 - journal.pda.org
Cleanroom microflora are of importance for microbiologists and quality control personnel in
order to assess changes in trends. Shifts in the types of microflora may indicate deviations …

[BOOK][B] Pharmaceutical microbiology: essentials for quality assurance and quality control

T Sandle - 2015 - books.google.com
… [3] Sandle T. The media kitchen: preparation and testing of microbiological culture media.
In… Sandle T. Sterility, sterilisation and sterility assurance for pharmaceuticals. Cambridge, UK: …

[BOOK][B] Sterility, sterilisation and sterility assurance for pharmaceuticals: technology, validation and current regulations

T Sandle - 2013 - books.google.com
Sandle, 2013 The right of Tim Sandle to be identified as author of this Work has been asserted
by him in accordance with sections 77 and 78 of the Copyright, Designs and Patents Act …

[PDF][PDF] Characterizing the microbiota of a pharmaceutical water system-a metadata study

T Sandle - SOJ Microbiology & Infectious Diseases, 2015 - researchgate.net
Bacterial populations inhabiting pharmaceutical grade water systems were investigated
over a fifteen year period. The systems analyzed were mains water, purified and Water-for-…

A review on biocide reduced susceptibility due to plasmid‐borne antiseptic‐resistant genes—special notes on pharmaceutical environmental isolates

R Vijayakumar, T Sandle - Journal of Applied Microbiology, 2019 - academic.oup.com
Biocides (antiseptics and disinfectants) are widely used in hospitals and pharmaceutical
industries for contamination control. The emergence of reduced susceptibility to biocides is the …

[HTML][HTML] Antimicrobial activity of silver-treated bacteria against other multi-drug resistant pathogens in their environment

DS Mohamed, RM Abd El-Baky, T Sandle, SA Mandour… - Antibiotics, 2020 - mdpi.com
Silver is a potent antimicrobial agent against a variety of microorganisms and once the
element has entered the bacterial cell, it accumulates as silver nanoparticles with large surface …

A novel mechanism of action of ketoconazole: inhibition of the NorA efflux pump system and biofilm formation in multidrug-resistant Staphylococcus aureus

RM Abd El-Baky, T Sandle, J John… - Infection and Drug …, 2019 - Taylor & Francis
Background The rapid emergence of antimicrobial resistance among Gram-positive organisms,
especially staphylococci, has become a serious clinical challenge. Efflux machinery and …

[HTML][HTML] Distribution of biocide resistant genes and biocides susceptibility in multidrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter …

R Vijayakumar, T Sandle, MS Al-Aboody… - Journal of infection and …, 2018 - Elsevier
Purposes The aim of this study was to determine the frequency of biocide resistant genes,
qacA, qacE and cepA in multidrug resistant (MDR) bacteria: Klebsiella pneumoniae, …

[PDF][PDF] Gram's stain: history and explanation of the fundamental technique of determinative bacteriology

T Sandle - IST Science and Technology, 2004 - researchgate.net
For those not familiar with Microbiology, the Gram stain (or more accurately Gram’s stain) is
a laboratory staining technique that distinguishes between two groups of bacteria by the …

[BOOK][B] Sterility, sterilisation and sterility assurance for pharmaceuticals

T Sandle, Sandle - 2013 - Elsevier
This chapter provides an introduction to the main themes of this book. It examines the theory
of sterility and how it is a concept of probability. Microorganisms and viability in relation to …