Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma
TY Yang, SC Chen, MW Leach, D Manfra… - The Journal of …, 2000 - rupress.org
Human herpesvirus 8 (HHV8, also known as Kaposi's sarcoma [KS]-associated herpesvirus)
has been implicated as an etiologic agent for KS, an angiogenic tumor composed of …
has been implicated as an etiologic agent for KS, an angiogenic tumor composed of …
Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice
SW Chensue, NW Lukacs, TY Yang, X Shang… - The Journal of …, 2001 - rupress.org
Chemokine receptors transduce signals important for the function and trafficking of leukocytes.
Recently, it has been shown that CC chemokine receptor (CCR)8 is selectively expressed …
Recently, it has been shown that CC chemokine receptor (CCR)8 is selectively expressed …
Emerging technologies to increase ligand binding assay sensitivity
SK Fischer, A Joyce, M Spengler, TY Yang, Y Zhuang… - The AAPS journal, 2015 - Springer
Ligand binding assays (LBAs) have been the method of choice for protein analyte measurements
for more than four decades. Over the years, LBA methods have improved in sensitivity …
for more than four decades. Over the years, LBA methods have improved in sensitivity …
[HTML][HTML] Immunogenicity assessment of AAV-based gene therapies: an IQ consortium industry white paper
T Yang, M Braun, W Lembke, F McBlane… - … Therapy-Methods & …, 2022 - cell.com
Immunogenicity has imposed a challenge to efficacy and safety evaluation of adeno-associated
virus (AAV) vector-based gene therapies. Mild to severe adverse events observed in …
virus (AAV) vector-based gene therapies. Mild to severe adverse events observed in …
2019 white paper on recent issues in bioanalysis: FDA immunogenicity guidance, gene therapy, critical reagents, biomarkers and flow cytometry validation (part 3 …
The 2019 13 th Workshop on Recent Issues in Bioanalysis (WRIB) took place in New
Orleans, LA, USA on April 1–5, 2019 with an attendance of over 1000 representatives from …
Orleans, LA, USA on April 1–5, 2019 with an attendance of over 1000 representatives from …
First-in-human study to assess guselkumab (anti-IL-23 mAb) pharmacokinetics/safety in healthy subjects and patients with moderate-to-severe psoriasis
…, E Bouman-Thio, P Szapary, TY Yang… - European journal of …, 2016 - Springer
Purpose The purpose of this study is to evaluate the pharmacokinetics, immunogenicity,
safety, and tolerability of guselkumab, a human monoclonal antibody with high affinity and …
safety, and tolerability of guselkumab, a human monoclonal antibody with high affinity and …
The Gfi-1B Proto-Oncoprotein Represses p21WAF1 and Inhibits Myeloid Cell Differentiation
B Tong, HL Grimes, TY Yang, SE Bear… - … and Cellular Biology, 1998 - Taylor & Francis
Gfi-1 is a cellular proto-oncogene that was identified as a target of provirus integration in T-cell
lymphoma lines selected for interleukin-2 (IL-2) independence in culture and in primary …
lymphoma lines selected for interleukin-2 (IL-2) independence in culture and in primary …
2020 White paper on recent issues in bioanalysis: Vaccine assay validation, qPCR assay validation, QC for CAR-T flow cytometry, NAb assay harmonization and …
B Corsaro, T Yang, R Murphy, I Sonderegger, A Exley… - Bioanalysis, 2021 - Future Science
The 14 th edition of the Workshop on Recent Issues in Bioanalysis (14 th WRIB) was held
virtually on June 15-29, 2020 with an attendance of over 1000 representatives from …
virtually on June 15-29, 2020 with an attendance of over 1000 representatives from …
2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 3–LBA, biomarkers and immunogenicity)
…, B Stouffer, N Tampal, A Torri, J Welink, TY Yang… - Bioanalysis, 2015 - Future Science
The 2015 9th Workshop on Recent Issues in Bioanalysis (9th WRIB) took place in Miami,
Florida with participation of 600 professionals from pharmaceutical and biopharmaceutical …
Florida with participation of 600 professionals from pharmaceutical and biopharmaceutical …
[HTML][HTML] Transcriptional regulation during p21WAF1/CIP1-induced apoptosis in human ovarian cancer cells
Q Wu, P Kirschmeier, T Hockenberry, TY Yang… - Journal of Biological …, 2002 - ASBMB
In this study we used adenovirus vector-mediated transduction of either the p53 gene (rAd-p53)
or the p21 WAF1/CIP1 gene (rAd-p21) to mimic both p53-dependent and -independent …
or the p21 WAF1/CIP1 gene (rAd-p21) to mimic both p53-dependent and -independent …