Dry powder inhalers: study of the parameters influencing adhesion and dispersion of fluticasone propionate

VNP Le, THH Thi, E Robins, MP Flament - Aaps Pharmscitech, 2012 - Springer
Interactions between particles are dependent on the physicochemical characteristics of the
interacting particles but it is also important to consider the manufacturing process. Blending …

Air permeability of powder: a potential tool for dry powder inhaler formulation development

VNP Le, E Robins, MP Flament - European Journal of Pharmaceutics and …, 2010 - Elsevier
Dry Powder Inhalers have drawn great attention from pharmaceutical scientists in recent years
in particular those consisting of low-dose micronized drug particles associated with larger …

Agglomerate behaviour of fluticasone propionate within dry powder inhaler formulations

VNP Le, E Robins, MP Flament - European Journal of Pharmaceutics and …, 2012 - Elsevier
Due to their small size, the respirable drug particles tend to form agglomerates which prevent
flowing and aerosolisation. A carrier is used to be mixed with drug in one hand to facilitate …

Influence of granulation and compaction on the particle size of ibuprofen—development of a size analysis method

VNP Le, P Leterme, A Gayot, MP Flament - International journal of …, 2006 - Elsevier
The aim of this work was to study the impact of the process on drug particle size. We chose
ibuprofen, practically insoluble in water, as granulometry greatly influences its dissolution rate…

In vitro evaluation of powders for inhalation: The effect of drug concentration on particle detachment

VNP Le, THH Thi, E Robins, MP Flament - International journal of …, 2012 - Elsevier
Limited information on the effect of the drug concentration on the performance of powders
for inhalation is currently published. The aim of this work was to study the influence of drug …

Influence of the lactose grade within dry powder formulations of fluticasone propionate and terbutaline sulphate

VNP Le, H Bierend, E Robins, H Steckel… - International journal of …, 2012 - Elsevier
Dry powder formulations are often composed of fine drug particles and coarser carrier particles,
typically alpha-lactose monohydrate. However, the performance of a powder formulation …

Aerosolization potential of cyclodextrins—Influence of the operating conditions

VNP Le, P Leterme, A Gayot… - PDA Journal of …, 2006 - journal.pda.org
The aim of this work is to characterize the aerosols obtained by jet nebulization with cyclodextrin
solutions and to study the influence of operating conditions on nebulization efficiency. …

[PDF][PDF] INFLUENCE OF POWDER MIXING PROCESS ON AGGLOMERATE BEHAVIOUR OF FLUTICASONE PROPIONATE WITHIN DRY POWDER INHALERS …

VNP Le, E Robins, MP Flament - pharmacompass.com
Dry Powder Inhalers (DPI) formulations are often composed of fine drug particles and inert
coarse carrier particles, typically α-monohydrate lactose. DPI formulation and production …

Biochemistry and physiology of a family of eel natriuretic peptides

Y Takei, RJ Balment - Fish Physiology and Biochemistry, 1993 - Springer
… ; le peptide atrial natriur6tique (ANP) dans l'atria, le peptide ventriculaire natriur6tique (VNP)
dans les ventricules et le peptide natriur6tique de type C dans le cerveau. Ces trois …

Can polarimetric Radarsat-2 images provide a solution to quantify non-photosynthetic vegetation biomass in semiarid mixed grassland?

Z Li, X Guo - Canadian Journal of Remote Sensing, 2017 - Taylor & Francis
… Radarsat-2 offre un nouveau moyen de quantifier la biomasse de la VNP. Cette étude … de
la VNP et la biomasse aérienne dans les prairies mixtes semi-arides. Les paramètres suivants …