The present study was carried out with a view to enhance dissolution rate of poorly water-soluble
drug aceclofenac (BCS-class II) using Avicel 200 and Sylysia 350 as polymers. Surface …

By an initial solvent screening of 18 solvents, 14 pure good solvents were selected for the
crystallization of tolbutamide. Solid generation by the solvent-change method was carried out …

The study investigates the combined influence of three independent variables in preparation
of aceclofenac ternary solid dispersion (SD) by kneading method. A 3-factor, 3-level Box-…

Bosentan is choice of drug for pulmonary arterial hypertension. It belongs to BCS class-II
category. Due to poor solubility in aqueous media, treatment leads to frequent dosing & …

Tolbutamide (TBM) is a first-generation sulphonylurea, used for treatment of non-insulin
dependent diabetes mellitus. Tolbutamide is practically insoluble in water and its dissolution is …

Objectives: To develop a stable formulation for self emulsifying drug delivery systems (SEDDS)
in order to enhance the solubility, rate and extent of drug release and oral bioavailability …

Objective The present research aims to integrate the concept of quality by design (QbD) to
develop galantamine HBr modified release pellets and to scrutinize the critical factors that can …

Aims of study:-The aim of the present study is to evaluate the protective effect of Amomum
subulatum seeds against experimentally induced liver injury. Materials and methods:-The …

Background: A combination of Glimepiride and Boswellia serrata extract reduces neuropathic
diabetic complications by reducing the peroxidase level and improving the antioxidant …

UHPLC-MS/MS was utilised to quantitatively analyse Rifampicin and Quercetin-loaded
Liquisolid compact in rat plasma. The UPLC Acquity C 18 (1.7 μm, 2.1 × 15 mm) column and 0.5 …