The poor aqueous solubility of carbamazepine was dramatically increased via complexation
with various chemically modified β-cyclodextrins and γ-cyclodextrins. A preparation of …

AIDS encephalopathy is an insidious complication of human immunodeficiency virus infection
which is difficult to treat because of the poor uptake of many potentially useful antiretroviral …

Complexation of carbamazepine with 2-hydroxypropyl-β-cyclodextrin was performed to
provide improved formulations of this widely used antiepileptic drug. Based on this approach, …

Prototype formulations of the progesterone derivatives pregnanolone and pregnenolone
were prepared by solubilizing the steroids in 2‐hydroxypropyl‐β‐cyclodextrin (HPβCD). The …

Orbital-cranial injuries have the greatest potential for death and disability of any condition
treated by the ophthalmologist. An object that penetrates through the orbit into the brain may …

The effects of aging and of food restriction at different times during life on rat adipocyte responses
to glucagon and epinephrine were explored by studying hormone-stimulated lipolysis, …

The structural parameters important for biologicalefficacy of an estradiol chemical delivery
system (CDS), a brain-targeting approach based on redox trapping, were examined by …

Studies were undertaken to determine the effects on body weight of a brain-enhanced chemical
delivery system for estradiol. This estradiol-chemical delivery system (E 2 -CDS) has a …

We have developed a redox system for brain-enhanced delivery of dexamethasone based
on an interconvertible dihydropyridine d= pyridinium salt carrier. Dexamethasone, when …

Objective: Improved therapy for AIDS dementia and related encephalopathies may be
achieved through enhanced delivery of effective antiretroviral agents to the central nervous …