Graft-versus-host disease (GVHD) represents a major hurdle impeding the efficacy of
allogeneic bone marrow transplantation (BMT). Bortezomib is a proteasome inhibitor that was …

Background: The open abdomen technique, after both military and civilian trauma, emergency
general or vascular surgery, has been used in some form for the past 30 years. There …

Although the need and benefit of prehospital interventions has been controversial for quite
some time, an increasing amount of evidence has stirred both sides into more frequent debate…

We measured the dissociation rate constants of the biotin/streptavidin and biotin/egg avidin
complexes by following the release of radiolabeled biotin from the preformed complexes in …

Purpose Characterize bortezomib pharmacokinetics/pharmacodynamics in relapsed myeloma
patients after single and repeat intravenous administration at two doses. Methods Forty-…

During the course of the last 30 years, several authors have contributed their clinical
experience to the literature in an effort to describe the various management strategies for the …

BACKGROUND: Reduced heart rate (HR) complexity (eg, a lack of randomness or unpatterned
variability) is an established predictor of trauma patient mortality. However, this finding …

Although nonneurologic organ dysfunction (NNOD) has been shown to significantly affect
mortality in subarachnoid hemorrhage, the contribution of NNOD to mortality after severe …

In his missionary journeys, St. Paul spoke in a number of cities in the Greek peninsula including
Athens, renowned for its philosophical heritage. He addressed to them the message of …

Background: A noninvasive tool reflecting intracranial hypertension (ICH) should prompt
early invasive monitoring and reduce secondary injury after traumatic brain injury. We …