The task of process research, namely developing efficient, economically and technically as
well as ecologically feasible syntheses in time, is demonstrated on the HIV-proteinase …

The quality-by-design (QbD) approach is widely utilized for developing and validating
manufacturing processes for drug substances as well as drug products. This paper discusses the …

The identification of critical process parameters in biologics and small molecule process
development is a key element of quality by design. The objectivity and consistency of …

2-Chloropyrimidine is converted to 2-cyanopyrimidine under very mild conditions in nearly
quantitative yield using 1, 4-diazabicyclo [2.2. 2] octane as catalyst. The development of the …

… Wolfgang Göhring* … Göhring head of synthesis Development Pharma technical
Development actives Basel Bldg. 86 room 705 Ch-4070 Basel tel.: +41 61 688 31 73 fax +41 …

I. Der Prasident A. von Zelewsky erMfnet urn 15.30 Uhr die Versammlung und begri. isst die
zah Ireich erschienenen Mitglieder und heisst sie in Visp willkommen. Er schliesst in diese …