Estimation of the degree of crystallinity of cefazolin sodium by X-ray and infrared methods

MS Kamat, T Osawa, RJ DeAngelis, Y Koyama… - Pharmaceutical …, 1988 - Springer
The pentahydrate (α form) of cefazolin sodium (CEZ) exhibited sharp X-ray diffraction peaks,
while the dehydrated α form showed weak but distinct diffraction peaks. As expected the …

Effect of solvent addition and thermal treatment on freeze drying of cefazolin sodium

Y Koyama, M Kamat, RJ De Angelis… - PDA Journal of …, 1988 - journal.pda.org
Due to the spontaneous and many times incomplete freezing of water upon supercooling
aqueous cefazolin sodium (CEZ) solutions, CEZ fails to crystallize readily. Unless thermally …

Biodistribution of gold nanoparticles in mice and investigation of their possible translocation by nerve uptake around the alveolus

Y Koyama, Y Matsui, Y Shimada… - The Journal of …, 2015 - jstage.jst.go.jp
The effect of nanoparticles in the environment on our health is a cause of concern. The
greatest concern with respect to the biological effect of nanoparticles is that they remain in the …

Community-acquired Acinetobacter baumannii meningitis in a previously healthy 14-month-old boy

…, M Suzuki, A Narita, Y Yamamoto, N Koyama… - Journal of infection and …, 2009 - Elsevier
We report a previously healthy 14-month-old boy who developed community-acquired
Acinetobacter baumannii meningitis. He had no history of immunodeficiency, and was brought to …

Demonstrating 100 Gbps optical packet switching using 16-bit longest prefix matching forwarding engine

…, H Harai, Y Kuroda, S Koyama - … Conference on Optical …, 2015 - ieeexplore.ieee.org
Wire-rate packet processing and its energy saving for over 100 Gbps speed of line are the
issues to resolve in optical packet switching. For that purpose, we have newly developed an …

Grades of 43 fish species in Japan based on IgE-binding activity

H Koyama, M Kakami, M Kawamura, R Tokuda… - Allergology …, 2006 - Elsevier
Background Hypersensitivity reactions to fish are a common food allergy, but IgE-binding
activity to fish species have not been fully elucidated. The aim of this study was to identify fish …

Local Structure and Spin State of Cobalt Ion at Defect in Lithium Overstoichiometric LiCoO2 As Studied by 6/7Li Solid-State NMR Spectroscopy

M Murakami, Y Noda, Y Koyama… - The Journal of …, 2014 - ACS Publications
Lithium overstoichiometric Li x CoO 2 (x > 1) with few phase transitions is promising as a
positive electrode material for lithium ion batteries; however, the detailed lithium local structures …

The characterization of gefitinib sensitivity and adverse events in patients with non-small cell lung cancer

N Koyama, Y Jinn, K Takabe, M Yoshizawa… - Anticancer …, 2006 - ar.iiarjournals.org
Background: Factors predicting gefitinib sensitivity and adverse events in non-small cell
lung cancer (NSCLC) remain controversial. Patients and Methods: Correlations among …

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice

S Tobisawa, Y Hozumi, S Arawaka, S Koyama… - Biochemical and …, 2003 - Elsevier
Mutations in a Cu, Zn-superoxide dismutase (SOD1) cause motor neuron death in human
familial amyotrophic lateral sclerosis (FALS) and its mouse model, suggesting that mutant …

Alteration of familial ALS-linked mutant SOD1 solubility with disease progression: its modulation by the proteasome and Hsp70

S Koyama, S Arawaka, R Chang-Hong, M Wada… - Biochemical and …, 2006 - Elsevier
Accumulation of misfolded Cu/Zn superoxide dismutase (SOD1) occurs in patients with a
subgroup of familial amyotrophic lateral sclerosis (fALS). To identify the conversion of SOD1 …