Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative …
…, L Ambrogio, D Auclair, J Wang, YK Song… - Cancer discovery, 2014 - AACR
Despite gains in survival, outcomes for patients with metastatic or recurrent rhabdomyosarcoma
remain dismal. In a collaboration between the National Cancer Institute, Children's …
remain dismal. In a collaboration between the National Cancer Institute, Children's …
[HTML][HTML] CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
Adoptive immunotherapy using chimeric antigen receptor (CAR) expressing T cells
targeting the CD19 B lineage receptor has demonstrated marked success in relapsed pre-B-cell …
targeting the CD19 B lineage receptor has demonstrated marked success in relapsed pre-B-cell …
[HTML][HTML] Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models
…, JY Chung, YK Song, K Desai… - The Journal of …, 2009 - Am Soc Clin Investig
Rhabdomyosarcoma (RMS) is a childhood cancer originating from skeletal muscle, and
patient survival is poor in the presence of metastatic disease. Few determinants that regulate …
patient survival is poor in the presence of metastatic disease. Few determinants that regulate …
The KSTAR project: An advanced steady state superconducting tokamak experiment
…, JC Sinnis, TG Brown, RB White, KM Young… - Nuclear …, 2000 - iopscience.iop.org
The Korea Superconducting Tokamak Advanced Research (KSTAR) project is the major
effort of the national fusion programme of the Republic of Korea. Its aim is to develop a steady …
effort of the national fusion programme of the Republic of Korea. Its aim is to develop a steady …
Characterization of Cationic Liposome-Mediated Gene Transfer In Vivo by Intravenous Administration
YK Song, F Liu, S Chu, D Liu - Human gene therapy, 1997 - liebertpub.com
Physicochemical properties of the cationic liposomes, including structure of the cationic lipids,
cationic lipid-to-DNA ratio, liposome particle size, and inclusion of the helper lipids, were …
cationic lipid-to-DNA ratio, liposome particle size, and inclusion of the helper lipids, were …
[HTML][HTML] Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium
PURPOSE Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood.
Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent …
Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent …
Factors in tissue handling and processing that impact RNA obtained from formalin-fixed, paraffin-embedded tissue
…, KM Hoffmann, M Kwon, YK Song… - … of Histochemistry & …, 2008 - journals.sagepub.com
Formalin-fixed, paraffin-embedded (FFPE) tissue is the most common specimen available for
molecular assays on tissue after diagnostic histopathological examination. RNA from FFPE …
molecular assays on tissue after diagnostic histopathological examination. RNA from FFPE …
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
The RAS isoforms are frequently mutated in many types of human cancers, including PAX3/PAX7
fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …
fusion-negative rhabdomyosarcoma. Pediatric RMS arises from skeletal muscle …
Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN-Not-Amplified Human Neuroblastoma
Purpose: High-risk neuroblastoma is an aggressive disease. DNA sequencing studies have
revealed a paucity of actionable genomic alterations and a low mutation burden, posing …
revealed a paucity of actionable genomic alterations and a low mutation burden, posing …
[HTML][HTML] Targeting wild-type and mutationally activated FGFR4 in rhabdomyosarcoma with the inhibitor ponatinib (AP24534)
SQ Li, AT Cheuk, JF Shern, YK Song, L Hurd, H Liao… - PloS one, 2013 - journals.plos.org
Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma. Despite
advances in modern therapy, patients with relapsed or metastatic disease have a very poor …
advances in modern therapy, patients with relapsed or metastatic disease have a very poor …