Luteolin inhibits ROS-activated MAPK pathway in myocardial ischemia/reperfusion injury

D Yu, M Li, Y Tian, J Liu, J Shang - Life Sciences, 2015 - Elsevier
Aims Luteolin is a falconoid compound that has an antioxidant effect, but its contribution to
ROS-activated MAPK pathways in ischemia/reperfusion injury is seldom reported. Here, we …

Antithrombotic activities of aqueous extract from Radix Ophiopogon japonicus and its two constituents

J Kou, Y Tian, Y Tang, J Yan, B Yu - Biological and pharmaceutical …, 2006 - jstage.jst.go.jp
… Junping KOU, Youqing TIAN,1) Yunkit TANG, Jin YAN, and Boyang YU* … We would like to
thank Fang Huang, Jia Wei, Yun Ni, Lin Xu, Na Li and Jie Tian for their assistance with the …

Investigation of the in vitro release of gentamicin from a polyanhydride matrix

…, S Chen, HC Chang, RM Liu, Y Tian… - Journal of controlled …, 2000 - Elsevier
Septacin™ is a sustained release formulation consisting of gentamicin sulfate dispersed in
a biodegradable polyanhydride matrix. The polyanhydride matrix is a copolymer of erucic …

In vitro characterization of polyorthoester microparticles containing bupivacaine

JS Deng, L Li, Y Tian, E Ginsburg… - Pharmaceutical …, 2003 - Taylor & Francis
Laboratory-scale spray-congealing equipment was utilized to fabricate injectable
microparticles consisting of polyorthoester and bupivacaine. Operating conditions for the spray-…

Sustained local drug delivery to the arterial wall via biodegradable microspheres

V Dev, N Eigler, MC Fishbein, Y Tian… - Catheterization and …, 1997 - Wiley Online Library
This study was designed to evaluate the feasibility of applying locally delivered polylactic
acid microspheres for drug delivery to the arterial wall. To study drug persistence, rhodamine‐…

The development of an injection-molding process for a polyanhydride implant containing gentamicin sulfate

…, L Li, J Setesak, L Claycomb, Y Tian… - PDA Journal of …, 2002 - journal.pda.org
A production-scale manufacturing process has been developed for polyanhydride/gentamicin
sulfate implants for the treatment of osteomyelitis. Gentamicin sulfate was first dried to an …

Effects of bpV (pic) and bpV (phen) on H9c2 cardiomyoblasts during both hypoxia/reoxygenation and H2O2-induced injuries

Y Tian, A Daoud, J Shang - Molecular medicine …, 2012 - spandidos-publications.com
Reactive oxygen species (ROS) are involved in myocardial injury. ROS are known to
inactivate lipid phosphatase and tension homolog on chromosome 10 (PTEN), an enzyme that …

Anti-thrombotic activity of DT-13, a saponin isolated from the root tuber of Liriope muscari

Y Tian, S Ma, B Lin, J Kou, B Yu - Indian Journal of Pharmacology, 2013 - journals.lww.com
Objective: To investigate the anti-thrombotic activity of DT-13 in experimental animal models.
Materials and Methods: The anti-thrombotic activity of DT-13 was evaluated by measuring …

Effect of γ-radiation on a polyanhydride implant containing gentamicin sulfate

JS Deng, L Li, D Stephens, Y Tian, FW Harris… - International journal of …, 2002 - Elsevier
Septacin™, a polyanhydride implant containing gentamicin sulfate, was sterilized by γ-radiation.
Its copolymer molecular weight (M w by GPC) was increased after this radiation. No …

Evaluation of microparticles containing doxorubicin suitable for aerosol delivery to the lungs

Y Tian, ME Klegerman, AJ Hickey - PDA Journal of Pharmaceutical …, 2004 - journal.pda.org
The efficacy of microparticulate systems containing anticancer agents may be assessed in
vitro prior to evaluation of the effects of targeted and controlled drug release on tumor growth. …