System for automated performance of the polymerase chain reaction

KB Mullis, L Johnson, RA Leath, TJ Wennberg… - US Patent …, 1997 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
27533926&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps

KB Mullis, L Johnson, RA Leath, TJ Wennberg… - US Patent …, 1994 - Google Patents
There is disclosed herein a machine for performing nucleic acid amplification under
computer control. The machine utilizes any one of a number of heating and cooling systems …

The nude mouse as a model for the study of human pancreatic cancer

FM Marincola, BJ Drucker, DY Siao, KL Hough… - Journal of Surgical …, 1989 - Elsevier
The purpose of this study was to characterize an in vivo model of human pancreatic cancer
suitable for chemotherapy and immunotherapy studies. In this study we report a 2-year …

Rapid identification of conditions, compounds, or compositions that inhibit, prevent, induce, modify, or reverse transitions of physical state

D Levinson - US Patent 7,108,970, 2006 - Google Patents
The invention concerns arrays comprising hundreds, thou sands, to hundreds of thousands
of samples and methods for screening thereof. These methods are useful to optimize, select …

Synthesis and screening combinatorial arrays of zeolites

PG Schultz, X Xiang, I Goldwasser - US Patent 6,649,413, 2003 - Google Patents
Methods and apparatus for the preparation and use of a substrate having an array of diverse
materials in predefined regions thereon. A substrate having an array of diverse materials …

Apparatuses and methods for creating and testing pre-formulations and systems for same

ED Carlson, P Cong, WH Chandler Jr… - US Patent …, 2005 - Google Patents
ASSistant Examiner Krishanan S Memon (57) ABSTRACT The invention provides methods,
apparatus, and Systems for performing high-throughput preparation and Screening of Salts …

Preparation and screening of crystalline zeolite and hydrothermally-synthesized materials

PG Schultz, X Xiang, I Goldwasser, G Briceno… - US Patent …, 2005 - Google Patents
Methods and apparatus for the preparation and use of a substrate having an array of diverse
materials in predefined regions thereon. A substrate having an array of diverse materials …

Combinatorial synthesis and screening of non-biological polymers

PG Schultz, XD Xiang, I Goldwasser, G Briceno… - US Patent …, 2006 - Google Patents
Methods and apparatus for the preparation and use of a substrate having an array of diverse
materials in predefined regions thereon. A substrate having an array of diverse materials …

Screening combinatorial arrays of inorganic materials with spectroscopy or microscopy

PG Schultz, X Xiang, I Goldwasser - US Patent 6,686,205, 2004 - Google Patents
Methods and apparatus for the preparation and use of a substrate having an array of diverse
materials in predefined regions thereon. A substrate having an array of diverse materials …

Preparation and screening of crystalline inorganic materials

PG Schultz, X Xiang, I Goldwasser, G Brice… - US Patent …, 2008 - Google Patents
Methods and apparatus for the preparation and use of a substrate having an array of diverse
materials in predefined regions thereon. A substrate having an array of diverse materials …