The exposure of proteins to light and the ensuing chemical and physical degradation has
been studied extensively for many years. The residues in proteins that undergo primary …

Recent oxidation events on monoclonal antibody candidates prompted us to investigate the
mechanism of oxidation of Met, Trp, and His residues and to search for suitable stabilizers …

The oxidation of free tryptophan (Trp) and Trp residues in peptides and proteins by
hydrogen peroxide as oxidative agent has been used to evaluate Trp losses and the pattern …

Fish fillet is a source of dietary protein with a well-balanced amino acid composition that also
contains high levels of B-vitamins and high levels of the trace elements selenium and iodide …

The rate at which a drug or other small solute interacts with a protein is important in
understanding the biological and pharmacokinetic behavior of these agents. One approach …

Binding by the drug imipramine to the protein human serum albumin (HSA) was studied by
using high-performance affinity chromatography. The association equilibrium constants and …

Abstract l-Tryptophan (l-Trp) is an amino acid important in nutrition, and mainly provided by
food supplements. However, it is known to be unstable under light irradiation, which is an …

There has been growing interest in the use of rapid and selective separation methods such
as high‐performance affinity chromatography (HPAC) or affinity capillary electrophoresis …

The oxidation of methionine residues in recombinant methionyl human granulocyte colony
stimulating factor with hydrogen peroxide has been investigated. Kinetic data of the …

Examining the chemical modification of biological polymers and the emerging applications
of this technology, Chemical Modification of Biological Polymers reflects the change in …