[BOOK][B] Lyophilization: introduction and basic principles
TA Jennings - 1999 - taylorfrancis.com
Finding consistent, analytical discussions of processes and principles of lyophilization can
be challenging and often frustrating. The first resource to gather information about the field …
be challenging and often frustrating. The first resource to gather information about the field …
Rapid determination of dry layer mass transfer resistance for various pharmaceutical formulations during primary drying using product temperature profiles
WY Kuu, LM Hardwick, MJ Akers - International journal of pharmaceutics, 2006 - Elsevier
Mass transfer resistance of the dry layer during the primary drying phase of a lyophilizaton
cycle is probably the most important factor affecting maximum product temperature and …
cycle is probably the most important factor affecting maximum product temperature and …
Optimization of secondary drying condition for desired residual water content in a lyophilized product using a novel simulation program for pharmaceutical …
T Kodama, M Takeuchi, N Wakiyama… - International journal of …, 2014 - Elsevier
The aim of this study was to optimize the shelf temperature and the drying time, mainly
dependent on the residual water content of a lyophilized product using a novel simulation …
dependent on the residual water content of a lyophilized product using a novel simulation …
Optimization of primary drying condition for pharmaceutical lyophilization using a novel simulation program with a predictive model for dry layer resistance
T Kodama, H Sawada, H Hosomi… - Chemical and …, 2014 - jstage.jst.go.jp
The purpose of this study was to develop a novel simulation program to accurately predict
the maximum product temperature and the primary drying time in lyophilization using the …
the maximum product temperature and the primary drying time in lyophilization using the …
Determination of mass transfer coefficients during freeze drying using modeling and parameter estimation techniques
WY Kuu, J McShane, J Wong - International journal of pharmaceutics, 1995 - Elsevier
An approach using mathematical modeling and parameter estimation techniques was
established to determine the best-fit mass transfer coefficients of the dried-layer resistance …
established to determine the best-fit mass transfer coefficients of the dried-layer resistance …
Determination for dry layer resistance of sucrose under various primary drying conditions using a novel simulation program for designing pharmaceutical lyophilization …
T Kodama, H Sawada, H Hosomi, M Takeuchi… - International journal of …, 2013 - Elsevier
Dry layer resistance, which is the resistance of dried cake against water vapor flow
generated from sublimation, is one of the important parameters to predict maximum product …
generated from sublimation, is one of the important parameters to predict maximum product …
Formulation Strategies for Recombinant Protein and Related Biotech Drugs
G Winter, J Myschik - Pharmaceutical Biotechnology: Drug …, 2012 - Wiley Online Library
As with practically all other drugs, biotec drugs are not stored or administered as such but as
formulations together with excipients. Since most of such biotec drugs need to be …
formulations together with excipients. Since most of such biotec drugs need to be …
Studio sperimentale sull'impatto del processo di spray freeze-drying sulla morfologia del prodotto finito= Experimental study on the product morphology obtained by …
AJ Clemente Ramirez - 2021 - webthesis.biblio.polito.it
SOMMARIO I prodotti farmaceutici hanno degli standard industriali sempre più rigorosi in
termini di sicurezza e salute del consumatore, richiedendo metodi di produzione sempre più …
termini di sicurezza e salute del consumatore, richiedendo metodi di produzione sempre più …
[PDF][PDF] The Effect of Excipients on Glass Transition Temperatures for
JW Jang, S Kitamura, JK Guillory - academia.edu
FK906, a tripeptide, has been used as a model compound to study the effect of excipients on
the glass transition temperature for peptides and related compounds in the frozen solution …
the glass transition temperature for peptides and related compounds in the frozen solution …
La liofilización:¿ ciencia o arte?
AMI Bartolomeu - Saber y Hacer, 2014 - revistas.usil.edu.pe
Podemos definir liofilização como um processo de estabilização, no qual uma substância é
previamente congelada e então a quantidade de solvente (geralmente água) é reduzida …
previamente congelada e então a quantidade de solvente (geralmente água) é reduzida …