Cyclodextrins (CDs) are synthetic substances obtained from the enzymatic degradation of
one of the most essential polysaccharides, starch. CDs belong to the family of cage …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Since their discovery over 100 years ago cyclodextrins (CDs) have been the subject of
numerous scientific publications. In 2016 alone CDs were the subject of over 2200 research …

Cyclodextrins are cyclic oligosaccharides which have recently been recognized as useful
pharmaceutical excipients. The molecular structure of these glucose derivatives, which …

Cyclodextrins are cyclic oligomers of glucose that can form water-soluble inclusion
complexes with small molecules and portions of large compounds. These biocompatible …

The second edition of this landmark volume continues the tradition of providing an extensive
compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes …

The objective of this Review is to summarize and critique recent findings and applications of
both unmodified and modified cyclodextrins for in vivo drug delivery. This review focuses on …

As the first pharmaceutical products which contain highly soluble cyclodextrin (CD)
derivatives (eg Sporanox™= itraconazole/HP-β-CD by Janssen and Clorocil™ …

Because of their bioadaptability and multi-functional characteristics, cyclodextrins (CDs) are
capable of alleviating the undesirable properties of drug molecules in various routes of …

Context: Ever since the discovery of cyclodextrins, a family of cyclic oligosaccharides based
on α (1→ 4) linkage among glucopyranose subunits, these versatile supramolecular hosts …