Formulations of sugars with amino acids or mannitol–influence of concentration ratio on the properties of the freeze-concentrate and the lyophilizate

B Lueckel, D Bodmer, B Helk… - Pharmaceutical …, 1998 - Taylor & Francis
Formulations consisting of either sucrose or trehalose with glycine, lysine–HCl, or mannitol
were studied to determine how the ratio of the excipients affects the design of the …

Mechanism of 2-hydropropyl-beta-cyclodextrin in the stabilization of frozen formulations

J Wong, JE Kipp, RL Miller, LM Nair, GJ Ray - European Journal of …, 2014 - Elsevier
Freezing of commonly used parenteral products to increase pharmaceutical stability for cost-
saving purposes is a common practice in patient care. However, frozen meropenem, a …

Microencapsulation of the renin inhibitor FK906 by phase separation of ethylcellulose in cyclohexane

G Weiss, H Yamaguchi, R Ibuki… - Journal of …, 1998 - Taylor & Francis
Microencapsulation of the renin inhibitor FK906 (tripeptide) by phase separation of
ethylcellulose in cyclohexane was performed to obtain sustained release of the drug for a …

[PDF][PDF] The Effect of Excipients on Glass Transition Temperatures for

JW Jang, S Kitamura, JK Guillory - academia.edu
FK906, a tripeptide, has been used as a model compound to study the effect of excipients on
the glass transition temperature for peptides and related compounds in the frozen solution …