Parenteral drug products are protected by appropriate primary packaging to protect against
environmental factors, including potential microbial contamination during shelf life duration …

ASTM F2338-09 Standard Test Method for Nondestructive Detection of Leaks in Packages
by Vacuum Decay Method is applicable for leak-testing rigid and semi-rigid non-lidded trays; …

An aerosol microbial ingress test was specifically designed and used to create a predictive
model in order to determine the maximum allowable leakage limit (MALL) of single-use …

A portable flexible container integrity test device for conducting integrity testing of flexible
containers is disclosed. The test device is particularly useful for testing aseptic flexible film …

The rational development of a physical test method to evaluate the microbial barrier
properties of sterile containers necessitates its correlation to microbiological exclusion. This …

The majority of parenteral drug products are manufactured in glass vials with an elastomeric
rubber stopper and a crimp cap. The vial sealing process is a critical process step during fill …

In the past, the packaging of pharmaceutical products often took little account of the
microbiological aspects of maintaining product integrity. This was especially true of …

Pharmaceutical packaging has allowed the widespread distribution of drugs; without it there
would be no pharmaceutical industry and the quality and quantity of life we have come to …

We present an accurate and reliable method for the detection of wall perforation during the
excimer-laser micro-drilling of glass ampoules and vials. The method is based on the …

During the pulsed-laser microdrilling process using nanosecond pulses, a plasma and a
shockwave develop. In order to study their formation and propagation and investigate the …