Nanopore technology for biomedical applications

TA Desai, DJ Hansford, L Kulinsky, AH Nashat… - Biomedical …, 1999 - Springer
The ability to create well-defined and controlled interfaces has been an area of great interest
over the last few years, particularly in the biomedical arena. This paper will describe the …

Protein concentration with single-pass tangential flow filtration (SPTFF)

C Casey, T Gallos, Y Alekseev, E Ayturk… - Journal of membrane …, 2011 - Elsevier
This paper presents a novel Cadence™ single-pass tangential flow filtration (SPTFF)
process for protein concentration, operating in a continuous mode. The main advantages of …

[BOOK][B] Biosimilars and Interchangeable Biologics: Tactical Elements

SK Niazi - 2016 - books.google.com
Even very established companies have made mistakes when developing biosimilar
products. For example, not appreciating future threats to intellectual property caused a …

[PDF][PDF] Introduction to tangential flow filtration for laboratory and process development applications

L Schwartz, K Seeley - Pall Corp, 2014 - academia.edu
Membrane filtration is a separation technique widely used in the life science laboratory.
Depending on membrane porosity, it can be classified as a microfiltration or ultrafiltration …

[BOOK][B] Membrane separations in biotechnology

WK Wang - 2001 - books.google.com
This text details the relationship between membrane technology and bioprocesses,
discussing applications. This second edition refines and optimizes key features of the first …

Clarification of transgenic milk using depth filtration

MA Perreault - US Patent 7,531,632, 2009 - Google Patents
Processes and apparati are provided for separating molecules of interest from a mixture by
depth filtration (DF). The DF of the invention is useful in the clarification and processing of …

[BOOK][B] Handbook of biogeneric therapeutic proteins: regulatory, manufacturing, testing, and patent issues

SK Niazi - 2002 - taylorfrancis.com
More than 20 billion dollars worth of biopharmaceuticals are scheduled to go off-patent by
2006. Given the strong political impetus and the development of technological tools that can …

Virus retentive filters

G Miesegaes, S Lute, H Aranha… - … , Bioseparation, and Cell …, 2009 - Wiley Online Library
Ensuring the absence of detectable viruses in biopharmaceutical products is imperative from
both a regulatory and patient safety standpoint. Biopharmaceutical viral safety is the result of …

Electroviscous effects in microchannels

L Kulinsky, Y Wang, M Ferrari - Micro-and Nanofabricated …, 1999 - spiedigitallibrary.org
Fluid flow in capillary microchannels is used in numerous applications in biotechnology
(such as protein separation, fast DNA analysis, drug deliveries systems and viral filtration), in …

Membrane filtration in animal cell culture

P Czermak, D Nehring, R Wickramasinghe - Animal cell biotechnology …, 2007 - Springer
Membrane filtration is frequently used in animal cell culture for bioreactor harvesting, protein
concentration, buffer exchange, virus filtration, and sterile filtration. A variety of membrane …