[HTML][HTML] Integrating plant molecular farming and materials research for next-generation vaccines

YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

Electrospun nanofibers for regenerative medicine

W Liu, S Thomopoulos, Y Xia - Advanced healthcare materials, 2012 - Wiley Online Library
Abstract This Progress Report reviews recent progress in applying electrospun nanofibers to
the emerging field of regenerative medicine. It begins with a brief introduction to …

Protein instability in poly (lactic-co-glycolic acid) microparticles

M van de Weert, WE Hennink, W Jiskoot - Pharmaceutical research, 2000 - Springer
In this review the current knowledge of protein degradation during preparation, storage and
release from poly (lactic-co-glycolic acid)(PLGA) microparticles is described, as well as …

Microspheres for controlled release drug delivery

NK Varde, DW Pack - Expert opinion on biological therapy, 2004 - Taylor & Francis
Controlled release drug delivery employs drug-encapsulating devices from which
therapeutic agents may be released at controlled rates for long periods of time, ranging from …

Fabrication of fillable microparticles and other complex 3D microstructures

KJ McHugh, TD Nguyen, AR Linehan, D Yang… - Science, 2017 - science.org
Three-dimensional (3D) microstructures created by microfabrication and additive
manufacturing have demonstrated value across a number of fields, ranging from …

Distinct phases of Polycomb silencing to hold epigenetic memory of cold in Arabidopsis

H Yang, S Berry, TSG Olsson, M Hartley, M Howard… - Science, 2017 - science.org
Gene silencing by Polycomb complexes is central to eukaryotic development. Cold-induced
epigenetic repression of FLOWERING LOCUS C (FLC) in the plant Arabidopsis provides an …

Development of highly porous large PLGA microparticles for pulmonary drug delivery

Y Yang, N Bajaj, P Xu, K Ohn, MD Tsifansky, Y Yeo - Biomaterials, 2009 - Elsevier
We report a new process of making highly-porous large polymeric microparticles for local
drug delivery to the lungs by inhalation. Poly (lactic-co-glycolic acid)(PLGA) microparticles …

Peroral Route:  An Opportunity for Protein and Peptide Drug Delivery

A Sood, R Panchagnula - Chemical Reviews, 2001 - ACS Publications
The better understanding of endogenous proteins, peptides, and peptidergic molecules and
their role in various body functions and pathological conditions in last few decades has …

The effect of a water/organic solvent interface on the structural stability of lysozyme

M van de Weert, J Hoechstetter, WE Hennink… - Journal of controlled …, 2000 - Elsevier
The effect of emulsification of lysozyme solutions with methylene chloride on protein
recovery and structural integrity was investigated. Total lysozyme recovery in the aqueous …

Microspheres for drug delivery

KK Kim, DW Pack - BioMEMS and Biomedical Nanotechnology: Volume I …, 2006 - Springer
With advances in biotechnology, genomics, and combinatorial chemistry, a wide variety of
new, more potent and specific therapeutics are being created. Because of common …