Plants and photosynthetic bacteria contain protein− molecular complexes that harvest
photons with nearly optimum quantum yield and an expected power conversion efficiency …

The objective of this study was to determine the individual contributions of ice formation,
solute concentration, temperature, and time, to irreversible protein denaturation during …

BACKGROUND: Camptothecin (CPT) is a well-established topoisomerase I inhibitor against
a broad spectrum of cancers. However, poor aqueous solubility, instability, and toxic effects …

Aspartate ammonia‐lyases (AALs) catalyze the non‐oxidative elimination of ammonia from l‐
aspartate to give fumarate and ammonia. In this work the AAL coding gene from …

The purpose of this research was to apply vacuum foam drying (VFD) for processing of
LaSota virus and to screen formulation additives for its stability. The aqueous dispersion of …

Aggregation of native proteins in solution is of fundamental importance with regard to both
the processing and the utilization of proteins. In the present work, a dynamic Monte Carlo …

The purpose of this research was to study isomalt as a protein-stabilizing excipient with
lactate dehydrogenase (LDH) during freeze-drying and subsequent storage and compare it …

The purpose of this study was to explore the cryoprotection mechanisms of high molecular
weight polyethylene glycols (PEGs)(eg, PEG 4000 and PEG 8000) on lactate …

Most biomolecules are quite stable in aqueous solutions for short periods of time. However,
a pharmaceutical product is expected to have adequate stability over a shelf life of typically …

The formation of poly (ethylene glycol)(PEG) hydrate during freeze–thawing of dilute lactate
dehydrogenase solutions with the addition of 0.05–160 mg/mL PEG 6000 is investigated by …