Particle engineering for pulmonary drug delivery

AHL Chow, HHY Tong, P Chattopadhyay… - Pharmaceutical …, 2007 - Springer
With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

Advances in pulmonary delivery of nanoparticles

G Kaur, RK Narang, G Rath… - Artificial Cells, Blood …, 2012 - Taylor & Francis
Nanotechnology has potential in the development of novel and effective delivery of drugs
within lungs. Different strategies have been utilized for pulmonary delivery of drugs …

[BOOK][B] Colloids in drug delivery

M Fanun - 2016 - taylorfrancis.com
Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a
number of challenging conditions, allowing researchers to cross barriers that have …

Inhalable nanostructured lipid particles of 9-bromo-noscapine, a tubulin-binding cytotoxic agent: In vitro and in vivo studies

K Jyoti, K Kaur, RS Pandey, UK Jain, R Chandra… - Journal of colloid and …, 2015 - Elsevier
Bromo-noscapine (9-Br-Nos) alters tubulin polymerization in non-small cell lung cancer cells
differently from noscapine. However, clinical applications of 9-Br-Nos are limited owing to …

Controlled delivery of inhaled therapeutic agents

AJ Hickey - Journal of controlled release, 2014 - Elsevier
There is increasing interest in the delivery of drugs to the lungs to treat a variety of diseases.
The spatial and temporal influence of deposition and clearance mechanisms on the fate of …

Inhalation delivery and anti-tumor activity of celecoxib in human orthotopic non-small cell lung cancer xenograft model

SV Fulzele, A Chatterjee, MS Shaik, T Jackson… - Pharmaceutical …, 2006 - Springer
Purpose To determine the in vivo anti-tumor effect of aerosolized Celecoxib (Cxb) in
combination with iv Docetaxel (Doc) and compare the anti-tumor effect with oral Cxb …

Efficacy versus safety concerns for aerosol chemotherapy in non-small-cell lung cancer: a future dilemma for micro-oncology

K Darwiche, P Zarogoulidis, NK Karamanos… - Future …, 2013 - Future Medicine
Inhaled chemotherapy was first used more than 30 years ago. Since then, numerous
chemotherapeutic agents have been used in either in vitro or in vivo studies. Several …

Anti-cancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549

SV Fulzele, MS Shaik, A Chatterjee… - Journal of pharmacy …, 2006 - academic.oup.com
Direct delivery of chemotherapeutic agents to the lung can increase both the drug
concentration and exposure period to lung tumours. The objective of this study was to …

[PDF][PDF] Pulmonary drug delivery: Implication for new strategy for pharmacotherapy for neurodegenerative disorders

N Islam, S Rahman - Drug Discoveries & Therapeutics, 2008 - researchgate.net
Innovative drug delivery in the treatment of brain neurodegenerative disorders such as
Parkinson's disease (PD) and Alzheimer's disease (AD) has the potential to avoid many …

Next generation dry powder inhalation delivery systems

AJ Hickey, TM Crowder - Inhalation Aerosols, 2006 - taylorfrancis.com
Dry powder inhalers have been through a number of periods of development over the last
half century. The first period of the 1960s and 1970s saw early passive inhalation devices …