Elemental impurities have been regulated in pharmaceutical products for many decades.
Metal impurities such as As, Cd, Cu, Pb, Hg, V and Pt in pharmaceuticals and drugs are …

Production of recombinant proteins generates a variety of process-related impurities. The
multistep manufacturing processes may introduce many potential contaminants into the final …

Biotherapeutics are exposed to common transition metal ions such as Cu (II) and Fe (II)
during manufacturing processes and storage. IgG1 biotherapeutics are vulnerable to …

The subject of the analysis of various elements, including metals and metalloids, in the
pharmaceutical industry has seen increasing importance in the last 10–15 years, as modern …

Elemental impurities may occur in pharmaceutical products under different conditions.
Impurity composition includes many types of species: metals and non-metals, which can be …

The plastics used in drug packaging systems and medical devices are composed of
homologous polymers and generally contain additives such as antioxidants, plasticizers and …

Vitamin D3 has numerous beneficial effects, such as musculoskeletal, immunomodulatory,
and neuroprotective. However, its instability is the main obstacle to formulating quality …

Natural pigments occur in plants as secondary metabolites and have been used as safe
colourants in food. Studies have reported that their unstable colour intensity might be related …

Elemental impurities determination in pharmaceuticals has become an emerging topic in the
last years due to the revision of the Chapter 231 from the United States Pharmacopeia by …

A new method has been developed using flow injection tandem mass spectrometry to semi-
quantitatively screen for weight loss drugs, including sibutramine, N-desmethylsibutramine …