Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems

J Cui, B Yu, Y Zhao, W Zhu, H Li, H Lou… - International journal of …, 2009 - Elsevier
Curcumin is a poorly water-soluble drug and its oral bioavailability is very low. A new self-
microemulsifying drug delivery system (SMEDDS) has been successfully developed to …

Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice

L Zhongfa, M Chiu, J Wang, W Chen, W Yen… - Cancer chemotherapy …, 2012 - Springer
Purpose Curcumin has shown a variety of biological activity for various human diseases
including cancer in preclinical setting. Its poor oral bioavailability poses significant …

Exemestane loaded self-microemulsifying drug delivery system (SMEDDS): development and optimization

AK Singh, A Chaurasiya, M Singh, SC Upadhyay… - Aaps Pharmscitech, 2008 - Springer
The purpose of this research work was to formulate and characterize self-micro emulsifying
drug delivery system containing exemestane. The solubility of exemestane was determined …

A critical appraisal of microemulsions for drug delivery: part II

B Sapra, P Thatai, S Bhandari, J Sood, M Jindal… - Therapeutic …, 2014 - Future Science
Microemulsions are thermodynamically stable, optically transparent isotropic solutions of oil
and water successfully formulated by using a combination of suitable surfactant and …

Lipid Nanoparticles Improve the Uptake of α-Asarone Into the Brain Parenchyma: Formulation, Characterization, In Vivo Pharmacokinetics, and Brain Delivery

P Ramalingam, P Ganesan, DS Prabakaran… - AAPS …, 2020 - Springer
Abstract Treatment of brain-related diseases is one of the most strenuous challenges in drug
delivery research due to numerous hurdles, including poor blood-brain barrier penetration …

Preparation and characterization of novel self nano emulsifying drug delivery system of allopurinol

P Patel, S Solanki, A Mahajan, F Mehta… - Research Journal of …, 2021 - indianjournals.com
The aim of research was to develop self nanoemulsifying drug delivery technology
containing low aqueous soluble drug allopurinol for improving solubility, dissolution and …

High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats

AK Singh, A Chaurasiya, GK Jain, A Awasthi, D Asati… - Talanta, 2009 - Elsevier
Bicalutamide is a non-steroidal antiandrogen and is an oral medication that is used for
treating prostate cancer. To evaluate the bioavailability of bicalutamide from bicalutamide …

Microemulsions: pharmaceutical applications

VB Patravale, AA Date - Microemulsions: Background, New …, 2009 - Wiley Online Library
Pharmaceutical research is aimed at delivery of the active pharmaceutical ingredient (API) to
the target organ at therapeutically relevant levels, with negligible discomfort and side effects …

Dissolution and bioavailability enhancement of alpha-asarone by solid dispersions via oral administration

L Deng, Y Wang, T Gong, X Sun… - Drug development and …, 2017 - Taylor & Francis
Abstract Alpha (α)-asarone (1-propenyl-2, 4, 5-methoxybenzol)(ARE) has been extensively
used to treat chronic obstructive pulmonary diseases (COPD), bronchial asthma …

A Comprehensive Insight on Self Emulsifying Drug Delivery Systems

R Kadian, A Nanda - Recent Advances in Drug Delivery and …, 2022 - ingentaconnect.com
Background: The oral route is a highly recommended route for the delivery of a drug. But
most lipophilic drugs are difficult to deliver via this route due to their low aqueous solubility …