Low aqueous solubility of active pharmaceutical ingredients presents a serious challenge in
the development process of new drug products. This article provides an overview on some …

Introduction: For poorly soluble compounds, a good bioavailability is typically needed to
assess the therapeutic index and the suitability of the compound for technical development …

Passive drug loading can be used to effectively identify suitable colloidal lipid carrier
systems for poorly water-soluble drugs. This method comprises incubation of preformed …

As an upshot of modern drug discovery techniques like combinatorial chemistry research
and inventive high throughput screening, number of new drug candidates developing, are …

When liposomes are used as drug delivery systems, it is important that the therapeutic agent
is efficiently and adequately encapsulated. In this study, cyclosporine A (CyA) was chosen …

The intravenous administration of poorly water‐soluble compounds is problematic.
Traditional formulation approaches, such as the use of co‐solvents, pH adjustment …