[HTML][HTML] Colon targeted drug delivery systems: a review on primary and novel approaches

AK Philip, B Philip - Oman medical journal, 2010 - ncbi.nlm.nih.gov
The colon is a site where both local and systemic delivery of drugs can take place. Local
delivery allows topical treatment of inflammatory bowel disease. However, treatment can be …

Controlled delivery of carvedilol nanosuspension from osmotic pump capsule: in vitro and in vivo evaluation

D Liu, S Yu, Z Zhu, C Lyu, C Bai, H Ge, X Yang… - International journal of …, 2014 - Elsevier
This study intended to develop a novel controlled delivery osmotic pump capsule of
carvedilol nanosuspension. The capsule is assembled using a semi-permeable capsule …

Asymmetric membrane in membrane capsules: a means for achieving delayed and osmotic flow of cefadroxil

AK Philip, K Pathak, P Shakya - European Journal of Pharmaceutics and …, 2008 - Elsevier
In the present study, both disintegrating and non-disintegrating polymeric capsular system in
achieving delayed as well as improved osmotic flow for the model drug cefadroxil was …

Osmotic capsules: a universal oral, controlled-release drug delivery dosage form

KC Waterman, GS Goeken, S Konagurthu… - Journal of controlled …, 2011 - Elsevier
An osmotic, oral, controlled-release capsule is described. This capsule provides drug
delivery at fixed delivery rates (T 80%= 6 or 14 h) independent of drug properties (eg …

Wet process-induced phase-transited drug delivery system: a means for achieving osmotic, controlled, and level A IVIVC for poorly water-soluble drug

AK Philip, K Pathak - Drug development and industrial pharmacy, 2008 - Taylor & Francis
A phase-transited, nondisintegrating, controlled release, asymmetric membrane capsular
system for poorly water-soluble model drug flurbiprofen was developed and evaluated both …

Osmotically regulated floating asymmetric membrane capsule for controlled site-specific delivery of ranitidine hydrochloride: Optimization by central composite design

MS Chauhan, A Kumar, K Pathak - AAPS PharmSciTech, 2012 - Springer
A nondisintegrating, floating asymmetric membrane capsule (FAMC) was developed to
achieve site-specific osmotic flow of a highly water-soluble drug, ranitidine hydrochloride …

Polymeric drug delivery approaches for colon targeting: A review

A Kaur, A Kaur, VP Kaur, M Kaur… - Drug Delivery …, 2014 - ingentaconnect.com
Colorectal cancer being a life style disease, number of cases is increasing day by day. Oral
drug delivery to treat colonic diseases encounters many problems like drug stability in the …

Recent advances in asymmetric membrane capsule based osmotic pump: a patent overview

A Patel, T Mehta, J Patel, M Patel… - Recent Patents on …, 2012 - ingentaconnect.com
Conventional drug delivery systems have little control over their drug release and almost no
control over the effective concentration at the target site. This kind of dosing pattern may …

Solubility-modulated asymmetric membrane tablets of triprolidine hydrochloride: statistical optimization and evaluation

R Dev, A Kumar, K Pathak - AAPS PharmSciTech, 2012 - Springer
The aim of the present study was to develop asymmetric membrane (AM) tablets for
controlled delivery of highly water-soluble antihistaminic drug triprolidine hydrochloride. The …

[PDF][PDF] Colon targeted drug delivery system-A review

A Dugad, P Nalawade, R Thakhre, S Kakade - J Curr Pharma Res, 2018 - academia.edu
Conventional drug therapies till date have proved its advantage for treating different
diseases. But still it has certain limitations such as non targeted drug delivery, high dose …