Pectin–an emerging new bioactive food polysaccharide

EG Maxwell, NJ Belshaw, KW Waldron… - Trends in Food Science & …, 2012 - Elsevier
Pectin is a constituent of the cell walls of fruits and vegetables, and provides an important
source of dietary fibre, as well as being a functional ingredient in processed foods. In …

Pectin based multi-particulate carriers for colon-specific delivery of therapeutic agents

S Das - International Journal of Pharmaceutics, 2021 - Elsevier
In case of colon-specific delivery of therapeutic agents through oral route, microbial/enzyme-
triggered release approach has several advantages over other approaches due to unique …

Local delivery of macromolecules to treat diseases associated with the colon

A Bak, M Ashford, DJ Brayden - Advanced drug delivery reviews, 2018 - Elsevier
Current treatments for intestinal diseases including inflammatory bowel diseases, irritable
bowel syndrome, and colonic bacterial infections are typically small molecule oral dosage …

The bioactivity of modified pectin fragments

VJ Morris, NJ Belshaw, KW Waldron… - … and Dietary Fibre, 2013 - Elsevier
This review discusses the structure of pectin, the effects of modification procedures used to
prepare modified pectins, and the evidence for the bioactivity of these modified materials. It …

Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation

S Regmi, S Pathak, MR Nepal, P Shrestha… - Journal of controlled …, 2019 - Elsevier
Enteric-coated formulations using Eudragit® polymers have been extensively used for
delivering drugs to the lower gastrointestinal tract. However, these drug-delivery systems …

Applications of natural polymeric materials in solid oral modified-release dosage forms

L Li, X Zhang, X Gu, S Mao - Current Pharmaceutical Design, 2015 - ingentaconnect.com
Solid oral modified-release dosage forms provide numerous advantages for drug delivery
compared to dosage forms where the drugs are released and absorbed rapidly following …

Preparation and evaluation of pectin-based colon-specific pulsatile capsule in vitro and in vivo

J Liu, L Zhang, Y Jia, W Hu, J Zhang… - Archives of pharmacal …, 2012 - Springer
The purpose of this study was to develop and evaluate a colon-specific, pulsatile drug
delivery system, which consists of an impermeable capsule body filled with a 5 …

An investigation into the characteristics of chitosan/Kollicoat SR30D free films for colonic drug delivery

H Wei, F Li-Fang, X Bai, L Chun-Lei, D Qing… - European journal of …, 2009 - Elsevier
The purpose of the study was to establish the physico-mechanical, digestibility, permeability
and swelling properties of chitosan/Kollicoat SR30D films as potential coatings for colonic …

Pectin/Kollicoat SR30D isolated films for colonic delivery [I]: a comparison of normal and colitis-induced models to assess the efficiency of microbially triggered drug …

H Wei, F Li-Fang, C Yong-Zhen, X Bai… - Journal of Pharmacy …, 2009 - academic.oup.com
Objectives The purpose of the study was to evaluate digestion of pectin/Kollicoat SR30D
free films for colonic delivery in vitro and in vivo. Methods Free films containing different …

改性果胶结构, 功能及方法的研究进展

张丽芬, 吴倩, 陈复生, 杨光胜 - 粮食与油脂, 2015 - cqvip.com
果胶是存在于高等植物初生细胞壁和中胞层中的一种酸性多糖, 因天然, 无毒且价廉而被广泛地
应用于食品与医药工业. 但是, 果胶由于分子量较大且不同来源果胶结构上的巨大差异而限制了 …