Innovative approaches in wound healing: trajectory and advances

MR Singh, S Saraf, A Vyas, V Jain… - … cells, nanomedicine, and …, 2013 - Taylor & Francis
Wound is one of the oldest suffering associated with the mankind and its history is as old as
humanity. Advances in the field of medical sciences created a pile of knowledge and paved …

Ceramic nanocarriers: versatile nanosystem for protein and peptide delivery

D Singh, P Dubey, M Pradhan… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Proteins and peptides have been established to be the potential drug
candidate for various human diseases. But, delivery of these therapeutic protein and …

Development of antibiotic and debriding enzyme-loaded PLGA microspheres entrapped in PVA-gelatin hydrogel for complete wound management

D Singh, MR Singh - Artificial Cells, Blood Substitutes, and …, 2012 - Taylor & Francis
A biocompatible moist system was developed for effective and complete wound healing.
Optimized PLGA microspheres of gentamicin (GM) and serratiopeptidase (STP) were …

A thermosensitive gel loaded with an enzyme and an antibiotic drug for the treatment of periprosthetic joint infection

E Sarıgöl, M Ekizoğlu, SB Pehlivan, E Bodur… - Journal of Drug Delivery …, 2018 - Elsevier
Biofilms have an important role in the pathogenesis of Periprosthetic Joint Infection (PJI) s
and are very likely the main cause in resistance to conventional treatments. In this study, a …

PLGA 微球载药量和包封率的影响因素及控制

孙美丽, 班俊峰, 黄思玉, 吕竹芬 - 广东药学院学报, 2011 - cqvip.com
PLGA 是乳酸和羟基乙酸的共聚物, 具有良好的生物相容性和生物可降解性,
已经广泛应用于缓控释给药系统的研究. 针对目前PLGA 微球存在载药量和包封率低的问题 …

聚乳酸-羟基乙酸共聚物载药微球性质及缓释行为的影响因素

安森博, 汪龙, 胡懿郃 - 中国医院药学杂志, 2016 - cqvip.com
聚乳酸-羟基乙酸共聚物(PLGA) 包裹药物制成缓释微球是药物缓释方向的研究热点, PLGA
微球作为载体, 具有良好的生物相容性和降解性, 但载药微球的性质和释药性能易受很多因素 …

[HTML][HTML] Comprehensive study of serratia peptidase immobilization from Serratia sp. ZF03 onto chitosan nanogels

N Salarizadeh, S Hasannia, RH Sajedi… - Turkish Journal of …, 2016 - degruyter.com
Objective In the present work, we have extended the study and immobilized the
metalloprotease enzyme in glutaraldehyde cross-linked chitosan nanogels to scrutinize the …

Tıbbi cihaz uygulamalarına bağlı olarak gelişen biyofilm bazlı osteomiyelit tedavisi için polimerik ilaç taşıyıcı sistemlerin formülasyonu ve değerlendirilmesi

E Sarigöl - 2013 - acikbilim.yok.gov.tr
Tıbbi cihaz uygulamalarına bağlı olarak gelişen biyofilm bazlı osteomiyelitte (BBMCKO),
biyofilm kullanılan antibiyotiklere karşı yüksek oranda direnç göstermekte ve antibiyotiğin …