HEMA in polymers with thermoresponsive properties
M Kasprów, D Lipowska-Kur, Ł Otulakowski… - Polymer …, 2021 - Taylor & Francis
This review presents the current state-of-knowledge concerning thermoresponsive
copolymers containing 2-hydroxyethyl methacrylate (HEMA). The thermoresponsive …
copolymers containing 2-hydroxyethyl methacrylate (HEMA). The thermoresponsive …
Feasibility of polymer-drug conjugates for non-cancer applications
AA Natfji, HMI Osborn, F Greco - Current opinion in colloid & interface …, 2017 - Elsevier
Polymer-drug conjugates have been intensely studied in the context of improving cancer
chemotherapy and yet the only polymer-drug conjugate on the market (Movantik®) has a …
chemotherapy and yet the only polymer-drug conjugate on the market (Movantik®) has a …
[HTML][HTML] Thermoresponsive P (HEMA-co-OEGMA) copolymers: Synthesis, characteristics and solution behavior
M Kasprów, J Machnik, Ł Otulakowski, A Dworak… - RSC …, 2019 - pubs.rsc.org
Random, thermoresponsive copolymers of 2-hydroxyethyl methacrylate (HEMA) and oligo
(ethylene glycol) methyl ether methacrylate Mn= 300 (OEGMA) were synthesized via atom …
(ethylene glycol) methyl ether methacrylate Mn= 300 (OEGMA) were synthesized via atom …
Poly (HEMA-Zidovudine) conjugate: a macromolecular pro-drug for improvement in the biopharmaceutical properties of the drug
A macromolecular pro-drug of a known anti-viral agent Zidovudine (AZT) was synthesized
and evaluated as a sustained drug delivery system. The pro-drug was synthesized by …
and evaluated as a sustained drug delivery system. The pro-drug was synthesized by …
[HTML][HTML] Pharmacological evaluation and preliminary pharmacokinetics studies of a new diclofenac prodrug without gastric ulceration effect
JL Dos Santos, V Moreira, ML Campos… - International journal of …, 2012 - mdpi.com
Long-term nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been associated with
several adverse effects such as gastric ulceration and cardiovascular events. Among the …
several adverse effects such as gastric ulceration and cardiovascular events. Among the …
Synthesis, characterization, and in vitro evaluation of new ibuprofen polymeric prodrugs based on 2-hydroxypropyl methacrylate
M Babazadeh, M Sheidaei, S Abbaspour… - Scientia …, 2013 - mdpi.com
The present research work describes the synthesis and evaluation of new acrylic-type
polymeric systems having degradable ester bonds linked to ibuprofen as materials for drug …
polymeric systems having degradable ester bonds linked to ibuprofen as materials for drug …
[HTML][HTML] Synthesis, In Vitro and In Vivo Evaluation of the N-ethoxycarbonylmorpholine Ester of Diclofenac as a Prodrug
The N-ethoxycarbonylmorpholine moiety was evaluated as a novel prodrug moiety for
carboxylic acid containing drugs represented by diclofenac (1). Compound 2, the N …
carboxylic acid containing drugs represented by diclofenac (1). Compound 2, the N …
A novel diclofenac-hydrogel conjugate system for intraarticular sustained release: Development of 2-pyridylamino-substituted 1-phenylethanol (PAPE) and its …
T Kawanami, LR LaBonte, J Amin… - International journal of …, 2020 - Elsevier
A local sustained-release drug delivery system, or depot, for intra-articular injection offers
the opportunity to release a therapeutic agent directly to the joint with limited need for …
the opportunity to release a therapeutic agent directly to the joint with limited need for …