Low solubility causing low dissolution in gastrointestinal tract is the major problem for drugs
meant for systemic action after oral administration, like cinnarizine. Pharmaceutical products …

Three-dimensional porous scaffolds are widely employed in tissue engineering and
regenerative medicine for their ability to carry bioactives and cells; and for their platform …

A nanofibrous matrix system (NFMS), consisting of a drug-loaded nanofiber layer, was
electrospun directly onto a polymeric backing film, the latter of which was formulated and …

Objectives The current studies entail successful formulation of optimized gastroretentive
tablets of lamivudine using the floating-bioadhesive potential of carbomers and cellulosic …

In order to overcome poor bioavailability of narrow absorption window drugs, a gastrosphere
system comprising two mechanisms of gastric retention, namely buoyancy and …

This study focused on developing a gastroretentive drug delivery system employing a triple-
mechanism interpolyelectrolyte complex (IPEC) matrix comprising high density, swelling …

Objectives: The objective of the study was to investigate the effect of iron oxide in the
development of mucoadhesive tablets of cinnarizine using Eudragit RLPO polymer. A …

This study aimed to develop a prolonged-release device for the potential site-specific
delivery of a neuroprotective agent (nicotine). The device was formulated as a novel …