Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials

J Bourquin, A Milosevic, D Hauser, R Lehner… - Advanced …, 2018 - Wiley Online Library
Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …

Biodegradable polymer nanogels for drug/nucleic acid delivery

Y Li, D Maciel, J Rodrigues, X Shi, H Tomas - Chemical reviews, 2015 - ACS Publications
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …

Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances

S Xu, BZ Olenyuk, CT Okamoto… - Advanced drug delivery …, 2013 - Elsevier
Targeting of drugs and their carrier systems by using receptor-mediated endocytotic
pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …

[HTML][HTML] Sustained drug release from smart nanoparticles in cancer therapy: A Comprehensive review

X Bai, ZL Smith, Y Wang, S Butterworth, A Tirella - Micromachines, 2022 - mdpi.com
Although nanomedicine has been highly investigated for cancer treatment over the past
decades, only a few nanomedicines are currently approved and in the market; making this …

Mesoscale nanoparticles selectively target the renal proximal tubule epithelium

RM Williams, J Shah, BD Ng, DR Minton, LJ Gudas… - Nano …, 2015 - ACS Publications
We synthesized “mesoscale” nanoparticles, approximately 400 nm in diameter, which
unexpectedly localized selectively in renal proximal tubules and up to 7 times more …

In vivo biodistribution and pharmacokinetics of silica nanoparticles as a function of geometry, porosity and surface characteristics

T Yu, D Hubbard, A Ray, H Ghandehari - Journal of controlled release, 2012 - Elsevier
The in vivo biodistribution and pharmacokinetics of silica nanoparticles (SiO2) with
systematically varied geometries, porosities, and surface characteristics were investigated in …

A new X-ray activated nanoparticle photosensitizer for cancer treatment

L Ma, X Zou, W Chen - Journal of biomedical nanotechnology, 2014 - ingentaconnect.com
Photodynamic therapy (PDT) has attracted ever-growing attention as a promising modality in
the treatment of cancer. However, due to the poor tissue penetration by light, PDT has rarely …

[HTML][HTML] Synthesis and characterization of diosgenin encapsulated poly-ε-caprolactone-pluronic nanoparticles and its effect on brain cancer cells

B Rabha, KK Bharadwaj, D Baishya, T Sarkar… - Polymers, 2021 - mdpi.com
Diosgenin encapsulated PCL-Pluronic nanoparticles (PCL-F68-D-NPs) were developed
using the nanoprecipitation method to improve performance in brain cancer (glioblastoma) …

The application of magnetic nanoparticles in the treatment and monitoring of cancer and infectious diseases

HM Williams - Bioscience Horizons: The International Journal of …, 2017 - academic.oup.com
Magnetic nanoparticles (MNPs) have shown promise in a number of biomedical
applications, including: magnetic hyperthermia, enhancing magnetic resonance imaging …