Enterprise-wide decision support applications have received increased attention in the
chemical process industry in the last decade. In this paper applications, which have real or …

This paper proposes knowledge-based assessment applied to Brazilian Toyota plants which
practice Lean manufacturing to evaluate work, production, and knowledge factors based on …

Covers a widespread view of Quality by Design (QbD) encompassing the many stages
involved in the development of a new drug product. The book provides a broad view of …

A workflow is an abstraction of the steps associated with the underlying work process and is
typically modeled as a directed graph. The workflow concept under its various …

This research examined current industry Knowledge Management (KM) methodologies and
capabilities in order to gain insights into the level of maturity and understanding of KM within …

This chapter discusses the role of knowledge management systems in providing a structured
framework for recording, using, and learning from the data that is generated over the life …

Process systems engineering, which in content if not in title has a history almost as old as
the chemical engineering discipline itself, can rightly be proud of having had a remarkable …

Key elements of pharmacokinetics (PK) studies include both, the number of sampling points
(NSP) as well as the spacing between the sampling points (SSP). Optimization of the SSP is …

The concept of design space is a key component of QbD implementation for pharmaceutical
products. ICH Q8 (R2) defines design space as “the multidimensional combination and …

Process systems engineering, which in content if not in title has a history almost as old as
the chemical engineering discipline itself, can rightly be proud of having had a remarkable …