The World Health Organization has named vaccine hesitancy as one of the top ten threats to
global health in 2019. The reasons why people choose not to vaccinate are complex, but …

Manufacturing has been the key factor limiting rollout of vaccination during the COVID‐19
pandemic, requiring rapid development and large‐scale implementation of novel …

Falsified medical products have become a global threat since they were first mentioned to
the general public at the conference of experts on the rational use of drugs organized by the …

The repertoire of complex proteins produced by the host cell during monoclonal antibody
(mAb) production has generated a bottleneck in downstream bioprocessing. Low ppm levels …

Currently, marketed influenza vaccines are only efficient against homologous viruses, thus
requiring a seasonal update based on circulating subtypes. This constant reformulation …

Live virus vaccine (LVV) purification, employing chromatography, can be challenged by low
binding capacities and elution yields. Alternatively, processes relying solely on enzymatic …

Aims Nucleic acids, particularly antibiotic resistance genes, are commonly found on surfaces
within healthcare environments, with levels not reducing following cleaning. Within the UK …

During the COVID‐19 pandemic, long development timelines typically associated with
vaccines were challenged. The urgent need for a vaccine provided a strong driver to …

The development of gene therapy products has been expanding globally, and among them,
the recombinant adeno-associated virus (rAAV) vector is one of the most promising vectors …

New influenza strains are constantly emerging, causing seasonal epidemics and raising
concerns to the risk of a new global pandemic. Since vaccination is an effective method to …