Liposome: composition, characterisation, preparation, and recent innovation in clinical applications

KS Ahmed, SA Hussein, AH Ali, SA Korma… - Journal of drug …, 2019 - Taylor & Francis
In the last decades, pharmaceutical interested researches aimed to develop novel and
innovative drug delivery techniques in the medical and pharmaceutical fields. Recently …

Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection

JJ López-Cano… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The development of ophthalmic formulations able to deliver hydrophilic and
hydrophobic drugs to the inner structures of the eye and restore the preocular tear film has …

Characterization and associated pressure-dependent behavior of deposits formed during sterile filtration of mRNA-Lipid nanoparticles

KO Messerian, A Zverev, JF Kramarczyk… - Journal of Membrane …, 2023 - Elsevier
The recent success of mRNA vaccines has generated increased interest in the use of Lipid
Nanoparticles (LNPs) for delivery of nucleic acids. The objective of this study was to …

Preclinical evaluations of Norcantharidin liposome and emulsion hybrid delivery system with improved encapsulation efficiency and enhanced antitumor activity

Z Liu, L Zhao, X Tan, Z Wu, N Zhou… - Expert Opinion on …, 2022 - Taylor & Francis
Background Norcantharidin (NCTD) has a certain degree of hydrophilicity and poor
lipophilicity, and has some side-effects, including short t1/2, vascular irritation, cardiotoxicity …

Pressure‐dependent fouling behavior during sterile filtration of mRNA‐containing lipid nanoparticles

KO Messerian, A Zverev… - Biotechnology and …, 2022 - Wiley Online Library
The COVID‐19 pandemic has generated growing interest in the development of mRNA‐
based vaccines and therapeutics. However, the size and properties of the lipid nanoparticles …

Regulatory science approach in pharmaceutical development of follow-on versions of non-biological complex drug products

DM Zagalo, S Simões, J Sousa - Journal of Pharmaceutical Sciences, 2022 - Elsevier
Scientific and technological breakthroughs in the field of Nanotechnology have been a
driving force throughout the development and approval of Non-Biological Complex Drugs …

Nanoarmour-shielded single-cell factory for bacteriotherapy of Parkinson's disease

X Zhou, Q Guo, M Guo, B Li, W Peng, D Wang… - Journal of Controlled …, 2021 - Elsevier
Cell-based therapy for Parkinson's disease (PD) is a novel and promising approach in
recent years. However, exogenous cells are easy to be captured and destroyed by the harsh …

Lipid-based vesicles: a non-invasive tool for transdermal drug delivery

A Raj, AN V, A Ivon, NNP P - Journal of Pharmaceutical Innovation, 2022 - Springer
The emergence of lipid nanovesicles (LNVs), like liposomes, transferosomes, and
ethosomes, strengthens transdermal drug delivery. The composition of lipid vesicles is …

[HTML][HTML] Imidazole-based pH-sensitive convertible liposomes for anticancer drug delivery

R Huang, V Gyanani, S Zhao, Y Lu, X Guo - Pharmaceuticals, 2022 - mdpi.com
In efforts to enhance the activity of liposomal drugs against solid tumors, three novel lipids
that carry imidazole-based headgroups of incremental basicity were prepared and …

Optimizing the filtration of liposomes using sterilizing-grade filters

K Zourna, A Iwaniec, S Turner, NB Jackson… - PDA Journal of …, 2021 - journal.pda.org
Liposomes are increasingly being investigated and implemented as injectable drug delivery
systems. The preferred method for sterilizing injectable drug formulations using liposomes is …