Liposome: composition, characterisation, preparation, and recent innovation in clinical applications
In the last decades, pharmaceutical interested researches aimed to develop novel and
innovative drug delivery techniques in the medical and pharmaceutical fields. Recently …
innovative drug delivery techniques in the medical and pharmaceutical fields. Recently …
Liposomes as vehicles for topical ophthalmic drug delivery and ocular surface protection
JJ López-Cano… - Expert opinion on …, 2021 - Taylor & Francis
Introduction: The development of ophthalmic formulations able to deliver hydrophilic and
hydrophobic drugs to the inner structures of the eye and restore the preocular tear film has …
hydrophobic drugs to the inner structures of the eye and restore the preocular tear film has …
Characterization and associated pressure-dependent behavior of deposits formed during sterile filtration of mRNA-Lipid nanoparticles
The recent success of mRNA vaccines has generated increased interest in the use of Lipid
Nanoparticles (LNPs) for delivery of nucleic acids. The objective of this study was to …
Nanoparticles (LNPs) for delivery of nucleic acids. The objective of this study was to …
Preclinical evaluations of Norcantharidin liposome and emulsion hybrid delivery system with improved encapsulation efficiency and enhanced antitumor activity
Z Liu, L Zhao, X Tan, Z Wu, N Zhou… - Expert Opinion on …, 2022 - Taylor & Francis
Background Norcantharidin (NCTD) has a certain degree of hydrophilicity and poor
lipophilicity, and has some side-effects, including short t1/2, vascular irritation, cardiotoxicity …
lipophilicity, and has some side-effects, including short t1/2, vascular irritation, cardiotoxicity …
Pressure‐dependent fouling behavior during sterile filtration of mRNA‐containing lipid nanoparticles
KO Messerian, A Zverev… - Biotechnology and …, 2022 - Wiley Online Library
The COVID‐19 pandemic has generated growing interest in the development of mRNA‐
based vaccines and therapeutics. However, the size and properties of the lipid nanoparticles …
based vaccines and therapeutics. However, the size and properties of the lipid nanoparticles …
Regulatory science approach in pharmaceutical development of follow-on versions of non-biological complex drug products
DM Zagalo, S Simões, J Sousa - Journal of Pharmaceutical Sciences, 2022 - Elsevier
Scientific and technological breakthroughs in the field of Nanotechnology have been a
driving force throughout the development and approval of Non-Biological Complex Drugs …
driving force throughout the development and approval of Non-Biological Complex Drugs …
Nanoarmour-shielded single-cell factory for bacteriotherapy of Parkinson's disease
X Zhou, Q Guo, M Guo, B Li, W Peng, D Wang… - Journal of Controlled …, 2021 - Elsevier
Cell-based therapy for Parkinson's disease (PD) is a novel and promising approach in
recent years. However, exogenous cells are easy to be captured and destroyed by the harsh …
recent years. However, exogenous cells are easy to be captured and destroyed by the harsh …
Lipid-based vesicles: a non-invasive tool for transdermal drug delivery
The emergence of lipid nanovesicles (LNVs), like liposomes, transferosomes, and
ethosomes, strengthens transdermal drug delivery. The composition of lipid vesicles is …
ethosomes, strengthens transdermal drug delivery. The composition of lipid vesicles is …
[HTML][HTML] Imidazole-based pH-sensitive convertible liposomes for anticancer drug delivery
In efforts to enhance the activity of liposomal drugs against solid tumors, three novel lipids
that carry imidazole-based headgroups of incremental basicity were prepared and …
that carry imidazole-based headgroups of incremental basicity were prepared and …
Optimizing the filtration of liposomes using sterilizing-grade filters
K Zourna, A Iwaniec, S Turner, NB Jackson… - PDA Journal of …, 2021 - journal.pda.org
Liposomes are increasingly being investigated and implemented as injectable drug delivery
systems. The preferred method for sterilizing injectable drug formulations using liposomes is …
systems. The preferred method for sterilizing injectable drug formulations using liposomes is …