Electrospinning nanofiber technology: a multifaceted paradigm in biomedical applications

A Garkal, D Kulkarni, S Musale, T Mehta… - New Journal of …, 2021 - pubs.rsc.org
Nanofibres are gaining significant popularity in biomedical applications. Advancement of
electrospinning setup and collector design has led to the use of nanofibers in biomedical …

Stimuli responsive and receptor targeted iron oxide based nanoplatforms for multimodal therapy and imaging of cancer: Conjugation chemistry and alternative …

N Dhas, R Kudarha, A Pandey, AN Nikam… - Journal of Controlled …, 2021 - Elsevier
Cancer being one of the most precarious and second most fatal diseases evokes
opportunities for multimodal delivery platforms which will act synergistically for efficient …

An overview of taste-masking technologies: approaches, application, and assessment methods

S Hu, X Liu, S Zhang, D Quan - AAPS PharmSciTech, 2023 - Springer
It is well-known that plenty of active pharmaceutical ingredients (API) inherently possess an
unpleasant taste, which influences the acceptance of patients, especially children …

Hot-melt extrusion: a roadmap for product development

MF Simões, RMA Pinto, S Simões - AAPS PharmSciTech, 2021 - Springer
Hot-melt extrusion has found extensive application as a feasible pharmaceutical
technological option over recent years. HME applications include solubility enhancement …

Exploring novel carrier for improving bioavailability of Itraconazole: Solid dispersion through hot-melt extrusion

A Chivate, A Garkal, K Hariharan, T Mehta - Journal of Drug Delivery …, 2021 - Elsevier
Abstract Kollicoat® Smartseal (Methyl methacrylate and diethylaminoethyl methacrylate
copolymer dispersion) which is used for taste masking and moisture protection, has shown …

Long-acting formulation strategies for protein and peptide delivery in the treatment of PSED

A Garkal, P Bangar, A Rajput, P Pingale, N Dhas… - Journal of Controlled …, 2022 - Elsevier
The invigoration of protein and peptides in serious eye disease includes age-related
macular degeneration, choroidal neovascularization, retinal neovascularization, and …

[PDF][PDF] Quality aspects in the development of pelletized dosage forms

S Agrawal, J Fernandes, F Shaikh, V Patel - Heliyon, 2022 - cell.com
The aim of this work was to identify and collate the major common challenges that arise
during pellet development. These challenges focus on aspects right from raw material …

[HTML][HTML] Cocrystals and drug–drug cocrystals of anticancer drugs: A perception towards screening techniques, preparation, and enhancement of drug properties

DD Kara, M Rathnanand - Crystals, 2022 - mdpi.com
The most favored approach for drug administration is the oral route. Several anticancer
drugs come under this category and mostly lack solubility and oral bioavailability, which are …

[HTML][HTML] Thin-film nanofibers for treatment of age-related macular degeneration

A Garkal, P Bangar, T Mehta - OpenNano, 2022 - Elsevier
AMD is the leading cause of blindness and is found in elderly patients. Lutein is a carotenoid
and has antioxidant properties hence acting as a neuroprotective in the macular region …

Development and in-vitro in-vivo characterization of in-situ gelling sustained-release nevirapine suspension

A Garkal, A Avachat - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Nevirapine is a BCS class-II drug used in the treatment and prevention of HIV/AIDS,
specifically HIV-1. This study was aimed to develop and evaluate a novel pH-responsive in …