Injectable protein-based medicinal products (drug products, or DPs) must be produced by
using sterile manufacturing processes to ensure product safety. In DP manufacturing the …

This work presents the primary drying phase of pharmaceutical lyophilization (freeze drying)
as a rarefied gas flow through a porous medium. The goal is to stimulate interest in this …

Intrahepatic cholestasis of pregnancy (ICP) is the most frequent pregnancy-specific liver
disease. It is characterized by pruritus and an accompanying elevation of serum bile acid …

For lyophilization applications, the selection of the primary container system (ie vial, stopper,
seal) must be given careful consideration in order to avoid surprises in the later stages of …

Die Schwangerschaftscholestase („intrahepatic cholestasis of pregnancy “, ICP) ist die
häufigste schwangerschaftsspezifische Lebererkrankung. Das Leitsymptom Juckreiz sowie …