Filling unit operation for biological drug products: Challenges and considerations

M Adler, A Allmendinger - Journal of Pharmaceutical Sciences, 2023 - Elsevier
One of the key unit operations during the aseptic fill-finish process of parenteral products,
such as biologics, is the filling process of the formulated, sterile filtered drug substance into …

Key factors controlling fibril formation of proteins

TTM Thu, HNT Phung, A Kloczkowski… - Acta Physica Polonica …, 2024 - appol.ifpan.edu.pl
Fibril formation resulting from protein aggregation is a hallmark of a large group of
neurodegenerative human diseases, including Alzheimer's disease, type 2 diabetes …