An enhancement of the glass surface chemical attack was shown in type I molded
borosilicate glass containers because of the synergy between the presence of complexing …

Among the factors that affect the glass surface chemical durability, pH and complexing
agents present in aqueous solution have the main role. Glass surface attack can be also …

Glass delamination, or the generation of glass flakes, continues to be an unwanted
occurrence in the manufacture of parenteral (injectable) solutions and suspensions. In this …

The delamination of pharmaceutical glass is a serious issue, as it can cause glass particles
to appear in vials, a problem that has forced a number of drug product recalls in recent …

Delamination, or the generation of glass flakes in vials used to contain parenteral drug
products, continues to be a persistent problem in the pharmaceutical industry. To …

Primary packaging containers used for the storage of parenteral drugs are designed to
protect the medicinal product from the environment to ensure patient safety. Mainly …

Glass delamination is characterized by the dissociation of glass flakes from the glass
surface. Since glass delamination is time dependent, 5 vial types were investigated to …

This paper is the result of two round robin activities run by the Technical Committee TC12,
Pharma Packaging, of the International Commission on Glass (ICG). It deals with the …

The occurrence of glass delamination is a serious concern for parenteral drug products.
Over the past several years, there has been a series of product recalls involving glass …

Glass is used as packaging material for parenteral formulation from years. Various untoward
occurrences have observed over the period of time with glass containers which leads to …