Advanced Virus Detection Technologies Interest Group (AVDTIG): efforts on high throughput sequencing (HTS) for virus detection

AS Khan, DA Vacante, JP Cassart, SHS Ng… - PDA journal of …, 2016 - journal.pda.org
Several nucleic-acid based technologies have recently emerged with capabilities for broad
virus detection. One of these, high throughput sequencing, has the potential for novel virus …

[HTML][HTML] LABRADOR—A Computational Workflow for Virus Detection in High-Throughput Sequencing Data

I Fabiańska, S Borutzki, B Richter, HQ Tran, A Neubert… - Viruses, 2021 - mdpi.com
High-throughput sequencing (HTS) allows detection of known and unknown viruses in
samples of broad origin. This makes HTS a perfect technology to determine whether or not …

[HTML][HTML] Current perspectives on high-throughput sequencing (HTS) for adventitious virus detection: upstream sample processing and library preparation

SH Ng, C Braxton, M Eloit, SF Feng, R Fragnoud… - Viruses, 2018 - mdpi.com
A key step for broad viral detection using high-throughput sequencing (HTS) is optimizing
the sample preparation strategy for extracting viral-specific nucleic acids since viral …

Report of the international conference on next generation sequencing for adventitious virus detection in biologicals

AS Khan, L Benetti, J Blumel, D Deforce, WM Egan… - Biologicals, 2018 - Elsevier
A fundamental aspect of biological product safety is to assure absence of adventitious
agents in the final product. Next-generation or high-throughput sequencing (NGS/HTS) has …

[HTML][HTML] Next-generation sequencing in clinical virology: Discovery of new viruses

S Datta, R Budhauliya, B Das, S Chatterjee… - World journal of …, 2015 - ncbi.nlm.nih.gov
Viruses are a cause of significant health problem worldwide, especially in the developing
nations. Due to different anthropological activities, human populations are exposed to …

[HTML][HTML] Current trends in diagnostics of viral infections of unknown etiology

D Kiselev, A Matsvay, I Abramov, V Dedkov, G Shipulin… - Viruses, 2020 - mdpi.com
Viruses are evolving at an alarming rate, spreading and inconspicuously adapting to cutting-
edge therapies. Therefore, the search for rapid, informative and reliable diagnostic methods …

Next-generation sequencing technologies in diagnostic virology

L Barzon, E Lavezzo, G Costanzi, E Franchin… - Journal of Clinical …, 2013 - Elsevier
The data deluge produced by next-generation sequencing (NGS) technologies is an
appealing feature for clinical virologists that are involved in the diagnosis of emerging viral …

A multicenter study to evaluate the performance of high-throughput sequencing for virus detection

AS Khan, SHS Ng, O Vandeputte, A Aljanahi, A Deyati… - Msphere, 2017 - Am Soc Microbiol
The capability of high-throughput sequencing (HTS) for detection of known and unknown
viruses makes it a powerful tool for broad microbial investigations, such as evaluation of …

Application of next generation sequencing for the detection of human viral pathogens in clinical specimens

J Parker, J Chen - Journal of Clinical Virology, 2017 - Elsevier
Background Next generation sequencing (NGS) is a new technology that can be used for
broad detection of infectious pathogens and is rapidly becoming an essential platform in …

[HTML][HTML] IABS/DCVMN webinar on next generation sequencing

AS Khan, S Theuns, L Mallet, G Cirefice, R Bhuller… - Biologicals, 2023 - Elsevier
Abstract Next Generation Sequencing (NGS) is a new technology that could overcome some
of the limitations of the current viral testing methods for demonstrating the absence of …