Aluminum in parenteral products: analysis, reduction, and implications for pediatric TPN

BE Rabinow, S Ericson, T Shelborne - PDA Journal of …, 1989 - journal.pda.org
Performance and cost of the best available analytical methodology for the measurement of
aluminum in parenteral products are presented. Typical levels of aluminum in representative …

Aluminum in pediatric parenteral nutrition products: measured versus labeled content

RL Poole, KP Pieroni, S Gaskari… - The Journal of …, 2011 - meridian.allenpress.com
ABSTRACT OBJECTIVE Aluminum is a contaminant in all parenteral nutrition solutions.
Manufacturers currently label these products with the maximum aluminum content at the …

Aluminum content in intravenous solutions for administration to neonates: role of product preparation and administration methods

SR de Oliveira, D Bohrer, SC Garcia… - Journal of Parenteral …, 2010 - Wiley Online Library
Background: Aluminum loading can reach toxic levels depending on the amount of
aluminum intake in intravenous solutions (IV). Premature infants are at a higher risk of …

[PDF][PDF] Aluminum contamination of parenteral nutrition solutions and its impact on the pediatric patient

GL Klein - Nutrition in clinical practice, 2003 - Citeseer
In the late 1970s and through the 1980s, aluminum was a timely topic for both research and
discussion in the medical community. Information was steadily acquired with regard to …

[CITATION][C] Aluminum contamination of parenteral nutrition fluids

JM Mirtallo - Journal of Parenteral and Enteral Nutrition, 2010 - Wiley Online Library
Aluminum Contamination/Mirtallo 347 leached from glass containers with rubber closures is
a significant contributor to aluminum present in parenteral products. 12, 13 In their article …

Aluminum in parenteral nutrition solution—sources and possible alternatives

WWK Koo, LA Kaplan, J Horn… - Journal of Parenteral …, 1986 - Wiley Online Library
The extent of aluminum (Al) contamination in parenteral nutrition (PN) solutions for infants is
not known. Aluminum was measured in 136 samples from various commercially available …

[HTML][HTML] An Assessment of aluminum contamination in neonatal parenteral nutrition solutions based on measured versus labeled content

HI Aljohar, RA Nawawi, NS Albanyan… - Saudi Pharmaceutical …, 2024 - Elsevier
Aluminum can potentially cause toxicity in pediatrics and neonates receiving parenteral
nutrition. Some PN solutions and ingredients in Saudi Arabia do not comply with US FDA …

Aluminum exposure from pediatric parenteral nutrition: meeting the new FDA regulation

RL Poole, SR Hintz, NI Mackenzie… - Journal of Parenteral …, 2008 - Wiley Online Library
Background: Aluminum toxicity can cause serious central nervous system and bone
toxicities. Aluminum is a contaminant of parenteral nutrition (PN) solution components …

Measured versus estimated aluminum content of parenteral nutrient solutions

RA Speerhas, DL Seidner - American Journal of Health-System …, 2007 - academic.oup.com
Purpose. A study was conducted to directly measure the aluminum concentration in a select
number of parenteral nutrient (PN) solutions and to compare this value with the calculated …

Parenteral drug products containing aluminum as an ingredient or a contaminant: response to Food and Drug Administration notice of intent and request for …

… /ASPEN Working Group on Standards for … - Journal of Parenteral …, 1991 - Wiley Online Library
Aluminum remains a significant contaminant of total parenteral nutrition (TPN) solutions and
may be elevated in bone, urine, and plasma of infants receiving TPN. Aluminum …