N-nitrosamines are chemical entities, some of which are considered to be possible human
carcinogens, which can be found at trace levels in some types of foods, tobacco smoke …

The potential for N-nitrosamine impurities in pharmaceutical products presents a challenge
for the quality management of medicinal products. N-Nitrosamines are considered cohort-of …

N-Nitrosamine risk assessment and control have become an integral part of pharmaceutical
drug product development and quality evaluation. Initial reports of nitrosamine …

Many nitrosamines have been recognized to be carcinogenic for many decades. Despite the
fact that several nitrosamine precursors are frequently used in the manufacturing of …

Various formulations of drugs containing aminopyramine, disulfiram or oxytetracycline were
analysed for volatile N-nitrosamines by gas chromatography using a chemiluminescence …

A number of selected drug formulations on the Canadian market were analyzed for A'-
nitrosodimethylamine (NDMA) and/Y-nitrosodiethylamine (NDEA) content by using a gas …

Nitrosamines have gained unexpected attention again, triggered by their discovery at
significant concentrations in some active pharmaceutical ingredients and pharmaceutical …

The current global situation of nitrosamine contamination has expanded from angiotensin-II
receptor blockers (ARBs) to wide range of medicines as the risk of contamination via the …

Abstratct N-nitrosamines are carcinogenic impurities most commonly found in groundwater,
treated water, foods, beverages and consumer products. The recent discovery of N …

Given that pharmaceutical excipients contain traces of nitrosating agents (NO x; eg, nitrites)
that are capable of reacting with amines to afford N-nitrosamines, N-nitrosamine risk …