Comparison of solute-binding properties of plastic materials used as pharmaceutical product containers

D Jenke, T Couch, A Gillum - PDA Journal of Pharmaceutical …, 2010 - journal.pda.org
Material/water equilibrium binding constants (Eb) were determined for 11 organic solutes
and 2 plastic materials commonly used in pharmaceutical product containers (plasticized …

Modeling of the solution interaction properties of plastic materials used in pharmaceutical product container systems

D Jenke, T Couch, A Gillum, S Sadain - PDA Journal of …, 2009 - journal.pda.org
Material/water equilibrium binding constants (Eb) were determined for 14 organic solutes
and 17 plastic raw materials that could be used in pharmaceutical product container …

Interactions between polymer containers and parenteral solutions: Correlating equilibrium polymer-water interaction constants with solute partition coefficients

DS Hayward, DR Jenke - International journal of pharmaceutics, 1990 - Elsevier
The interaction between six polymeric materials (current or candidate parenteral product
containers) and eight test marker solutes was evaluated. Test marker compounds used …

Evaluation of the general solution compatibility of polymer materials used in medical devices such as syringes

D Jenke, A Odufu, T Couch, M Chacko… - PDA journal of …, 2012 - journal.pda.org
The general compatibility between various polymers (plastic and elastomeric materials)
commonly used in medical devices (eg, syringes) and common solution-based …

Evaluation of various solvent systems for modeling solute sorption with plasticized polyvinyl chloride materials

DR Jenke - Journal of pharmaceutical sciences, 1993 - Elsevier
The partitioning behavior of 16 chemically diverse model solutes was determined for four
model solvents (octanol, hexane, heptane, and chloroform) and two components of …

Effect of solution phase composition on the interaction between aqueous model solutes and polymeric container materials

DR Jenke - Pharmaceutical research, 1991 - Springer
The interaction between several marker solutes and a polyolefin laminate polymer was
studied in several solutions. Solutions studied included mixtures of sodium chloride and …

Liquid chromatographic measurement of solute solvent/solvent partition coefficients: application to solute/container interactions

DR Jenke, DS Hayward… - Journal of chromatographic …, 1990 - academic.oup.com
Octanol—water partition coefficients (P ow) for model compounds used to study solute—
polymer interactions are determined by reversed-phase high-performance liquid …

The effect of solvent polarity on the accumulation of leachables from pharmaceutical product containers

D Jenke, A Odufu, M Poss - European journal of pharmaceutical sciences, 2006 - Elsevier
Material/water equilibrium interaction constants (Eb) were determined for 12 organic model
solutes and a plastic material used in pharmaceutical product containers (non-PVC …

Interactions between polymer containers and parenteral solutions: the correlation of equilibrium constants for polymer-water partitioning with octanol-water partition …

DS Hayward, RA Kenley, DR Jenke - International journal of pharmaceutics, 1990 - Elsevier
Polymer-water equilibrium binding constants (EB) were determined for twelve organic
solutes in contact with a composite polyolefin polymer. The polymer studied is a proprietary …

Evaluation of the chemical compatibility of plastic contact materials and pharmaceutical products; safety considerations related to extractables and leachables

D Jenke - Journal of pharmaceutical sciences, 2007 - Elsevier
ABSTRACT A review is provided on the general topic of the compatibility of plastic materials
with pharmaceutical products, with specific emphasis on the safety aspects associated with …