A multi-layered, laminated plastic material, similar to those used in flexible intravenous
solution containers, was loaded to contain known amounts of 15 model compounds whose …

Plastic materials are widely used in medical items, such as solution containers, transfusion
sets, transfer tubing, and devices. An emerging trend in the biotechnology industry is the …

Plastic materials are widely used in medical items, such as solution containers, transfusion
sets, transfer tubing and devices. An emerging trend in the biotechnology industry is the …

The accumulation of organic compounds associated with plastic materials into
pharmaceutical products and their associated solutions has important suitability for use …

Material/water equilibrium interaction constants (Eb) were determined for 12 organic model
solutes and a plastic material used in pharmaceutical product containers (non-PVC …

While the ability of packaging systems to contribute leached substances to finished drug
products is well established, increasing interest is being focused on the potential …

This study examines the impact, from a leachables perspective, of charging a solution
contact component of a polymeric solution container. By charging such a container …

The interaction between a medical device and a pharmaceutical solution it contacts may
dictate solution safety and/or efficacy. Of specific concern is the ability of device components …

A review is provided, related to the chromatographic methods used to assess the
accumulation of leachable substances from packaging materials used for pharmaceutical …

Full article: Validation of a Liquid Chromatographic Method for Quantitation of Organic
Compounds Leached from a Plastic Container into a Pharmaceutical Formulation Skip to …