Solubility Concepts and Their Applications to the Formulation of Pharmaceutical Systems |
PDA Journal of Pharmaceutical Science and Technology Skip to main content Main menu …

Solubility is defined as the maximum quantity of a substance that can be completely
dissolved in a given amount of solvent, and represents a fundamental concept in fields of …

Solubility is one of the most important physicochemical properties studied during
pharmaceutical preformulation. For liquid dosage form development, accurate solubility data …

The solubility of a drug is one of its most important physicochemical properties. The
determination of drug solubility and ways to alter it, if necessary, are essential components …

Identification of lead compounds with higher molecular weight and lower aqueous solubility
has become increasingly prevalent with the advent of high throughput screening. Poor …

Publisher Summary The solubility of a drug is one of its most important physico-chemical
properties. The determination of drug solubility and ways to alter it, if necessary, are …

This book describes the physicochemical fundamentals and biomedical principles of drug
solubility. Methods to study and predict solubility in silico and in vitro are described and the …

Solubility of a drug/drug candidate is one of the most important required physico-chemical
properties in pharmaceutical area and nearly 40% of drug candidates fail to proceed to the …

Organic solvents are amongst the most powerful solubilization agents for a large number of
water-insoluble drugs. A number of equations has been reported for mathematical …

The use and potential of solubility parameters for pharmaceutical dosage form design are
reviewed in this paper. Specific reference is given to the development of the approach, its …