Apparent binding affinity and capacity of daunomycin to the acidic phospholipids cardiolipin,
phosphatidylglycerol, phosphatidic acid, phosphatidylserine and phosphatidylinositol, and …

Membrane-model systems (monolayers, small unilamellar vesicles) were used to study the
interaction between adriamycin (ADM) and phospholipids. Adsorption of 3 H-labeled …

Department of Neurochemistry, School of Medicine, University of Alicante, 03080 Alicante,
Spain Received December 6, 1989; Revised Manuscript Received March 26, 1990 abstract …

Drug-membrane association of daunomycin, adriamycin and three of its derivatives,
adriamycin-14-octanoate (AD-14-OCTA), adriamycin-14-acetate (AD-14-ACE) and N …

The impressive affinity of Adriamycin and related anthracycline antibiotics for negatively-
charged phospholipids has been implicated in the mechanism of the cardiac toxicity of these …

< 正> Biomembrane, according to our present view, consists of a lipid bilayer matrix with
which membrane-bound proteins are associated. There is a widening belief that membrane …

The binding of the cytotoxin adriamycin (doxorubicin) to phospholipids, DNA, and RNA was
investigated using (i) fluorescence quenching by this drug of liposomes containing pyrene …

The interaction of adriamycin with lipids was studied in model (monolayers, small
unilamellar vesicles, large multilamellar vesicles) and natural (chinese hamster overy cell) …

The cytotoxic effects observed for nonpenetrating, polymerimmobilized
anthracycline'strongly suggest that the interaction of the drugs with the plasma membrane of …

The sensitivity of the keto and carbonyl infrared bands of daunomycin (DNM) to hydrogen
bonding with the solvent, has been used to study the effect of the physical state and lipid …