Automated Limulus Amebocyte Lysate (LAL) Test for Endotoxin Analysis using a Mew Toxinometer ET-201

H Oishi, A Takaoka, Y Hatayama, T Matsuo… - PDA Journal of …, 1985 - journal.pda.org
A precise, efficient, automated method to perform Limulus Amebocyte Lysate (LAL) tests has
been developed by using a new Toxinometer ET-201, which measures the turbidity change …

Endotoxin Detection in Pharmaceuticals and Medical Devices with Kinetic-QCL a Kinetic-Quantitative Chromogenic Limulus Amebocyte Lysate Assay

RN Berzofsky - ALTEX-Alternatives to animal experimentation, 1995 - altex.org
The observation that endotoxin caused gelation in extracts of Limulus amebocytes has been
expanded to the development of an in vitro kinetic, quantitative chromogenic LAL assay …

An automated analysis system of Limulus amebocyte lysate (LAL)-endotoxin reaction kinetics using turbidimetric kinetic assay

H OISHI, M FUSAMOTO, Y HATAYAMA… - Chemical and …, 1988 - jstage.jst.go.jp
抄録 An automated analysis system for evaluating reaction kinetics between Limulus
amebocyte lysate (LAL) and endotoxin has been developed by using a data acquisition …

Quantitative endotoxin determination. Automated kinetic Limulus amebocyte lysate microtiter test with measurement of sample-related interferences

B Ditter, KP Becker, R Urbaschek… - Arzneimittel …, 1983 - europepmc.org
A turbidometric, automated limulus amoebocyte lysate (LAL) microtiter test has been
developed based on the evaluation of the LAL-endotoxin reaction kinetics. The maximal …

Comparison of Limulus amebocyte lysate test methods for endotoxin measurement in protein solutions

L Chen, N Mozier - Journal of pharmaceutical and biomedical analysis, 2013 - Elsevier
The measurement of low levels of bacterial lipopolysaccharides (endotoxins) in protein
samples can be a challenge due to potential interference from the inherent properties of the …

New microassay for quantitation of endotoxin using Limulus amebocyte lysate combined with enzyme-linked immunosorbent assay

GH Zhang, L Baek, C Koch - Journal of clinical microbiology, 1988 - Am Soc Microbiol
A combined method of the Limulus amebocyte lysate (LAL) test and the enzyme-linked
immunosorbent assay for quantitation of endotoxin was developed based on our …

Detection of endotoxin in biological products by the limulus test.

JF Cooper, SM Pearson - Developments In Biological …, 1977 - europepmc.org
The limulus amebocyte lysate (LAL) test is established as a beneficial quality assurance
measure for the parenteral drug industry because of its sensitivity, specificity, and simplicity …

Limulus amebocyte lysate (LAL) detection of endotoxin in human blood

TJ Novitsky - Journal of Endotoxin Research, 1994 - journals.sagepub.com
Limulus amebocyte lysate (LAL) has been applied to the detection of endotoxin in human
serum, plasma and blood since the early 1970s. Although the diagnostic potential of LAL for …

Single-step, chromogenic Limulus amebocyte lysate assay for endotoxin

GK Lindsay, PF Roslansky… - Journal of clinical …, 1989 - Am Soc Microbiol
A new reagent for the chromogenic Limulus amebocyte lysate (LAL) assay is described. LAL
was formulated for optimal performance in either an endpoint procedure or a kinetic …

Automation of chromogenic substrate Limulus amebocyte lysate assay method for endotoxin by robotic system

K Tsuji, PA Martin, DM Bussey - Applied and environmental …, 1984 - Am Soc Microbiol
The chromogenic substrate Limulus amebocyte lysate (LAL) assay method for the detection
of endotoxin was automated by a Zymate robotic system. The software developed enables …