Lentiviral Vector–Mediated Genetic Modification of Cell Substrates for the Manufacture of Proteins and Other Biologics
L Baranyi, A Roy, HD Embree… - PDA Journal of …, 2010 - journal.pda.org
Transduction with Lentiviral vectors has been shown to be the most efficient method for the
stable delivery of nucleic acid sequences into mammalian cells. Lentiviral vectors have been …
stable delivery of nucleic acid sequences into mammalian cells. Lentiviral vectors have been …
Stable expression by lentiviral transduction of cells
N Gödecke, H Hauser, D Wirth - Recombinant Protein Expression in …, 2018 - Springer
Lentiviral gene transfer represents a versatile and powerful method for genetic transduction
of many cell lines and primary cells including “hard-to-transfect” cells. As a consequence of …
of many cell lines and primary cells including “hard-to-transfect” cells. As a consequence of …
Lentiviruses as gene transfer agents for delivery to non-dividing cells
L Naldini - Current opinion in biotechnology, 1998 - Elsevier
Lentiviral vectors are proving to be effective agents for the direct delivery and sustained
expression of a transgene in several tissues, including brain, retina, muscle and liver …
expression of a transgene in several tissues, including brain, retina, muscle and liver …
[HTML][HTML] Gene delivery by lentivirus vectors
AS Cockrell, T Kafri - Molecular biotechnology, 2007 - Springer
The capacity to efficiently transduce nondividing cells, shuttle large genetic payloads, and
maintain stable long-term transgene expression are attributes that have brought lentiviral …
maintain stable long-term transgene expression are attributes that have brought lentiviral …
Novel lentiviral vectors for human gene therapy
B Dropulic - Expert opinion on investigational drugs, 1998 - Taylor & Francis
This review summarises an emerging viral vector system for use in human gene therapy-
lentiviral vectors. Lentiviral vectors have several advantages over existing viral vectors. They …
lentiviral vectors. Lentiviral vectors have several advantages over existing viral vectors. They …
Production of high-titer lentiviral particles for stable genetic modification of mammalian cells
Lentiviral gene transfer technologies exploit the natural efficiency of viral transduction to
integrate exogenous genes into mammalian cells. This provides a simple research tool for …
integrate exogenous genes into mammalian cells. This provides a simple research tool for …
Lentiviral vectors: optimization of packaging, transduction and gene expression
C Delenda - The Journal of Gene Medicine: A cross …, 2004 - Wiley Online Library
Gene transfer vectors based on retroviruses including oncogenic retroviruses and
lentiviruses provide effective means for the delivery, integration and expression of …
lentiviruses provide effective means for the delivery, integration and expression of …
Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy
Lentiviral vectors are tools for gene transfer derived from lentiviruses. From their first
application to now they have been strongly developed in design, in biosafety and in their …
application to now they have been strongly developed in design, in biosafety and in their …
Production of lentiviral vectors in protein‐free media
H Kuroda, MP Marino, RH Kutner… - Current Protocols in Cell …, 2011 - Wiley Online Library
The use of lentiviral vectors for transgene delivery in vitro and in vivo for applications in
neuroscience, hematology, developmental biology, stem cell biology, and transgenesis has …
neuroscience, hematology, developmental biology, stem cell biology, and transgenesis has …
Lentiviral transgenesis-a versatile tool for basic research and gene therapy
A Pfeifer - Current gene therapy, 2006 - ingentaconnect.com
Transgenic animals are of outstanding relevance for medical sciences, because they can be
used to model human diseases and to develop gene therapy strategies. A recent …
used to model human diseases and to develop gene therapy strategies. A recent …
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